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Figure 1.
Figure 1. Structure of impb449. (a) Stereo view of impb449
dimer in the asymmetric unit. The crystal structure of the
impb449 molecules forms a dimer, which is composed of molecule
I(pink) and II(green) in the asymmetric unit. Three interaction
sites for dimer formation are depicted by the ball-and-stick
model. The C-terminal area interaction is in purple, and the
second and third interaction sites are in blue and red,
respectively. (b) HEAT repeat helices in impb449. The convex
side of helices of A1-A10 and the concave side of the helices of
B1-B10 and 3[10] helices are colored in blue, red and light
blue, respectively. C2 helix is colored in green. (c) Structural
alignment of the ten HEAT repeats of impb449. The first amino
acid residue of each repeat is indicated on the left. Each
repeat contains helix A and B. The repeat 2 contains helix C.
Underlined residues in repeats 3, 4, and 5 comprise 3[10]
helices indicated in (b).
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