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Figure 1.
Figure 1. Structures of 1D7 versus WT. (a) Stereoview of an
ensemble of the 20 lowest energy structures of 1D7. Sidechains
of core residues are displayed in green and the N and C termini
are labeled. (b) Superposition of the structure of 1D7 closest
to the mean (blue) with the crystal structure (red; accession
code 1UBI [15]) the coordinates of which were used for the
design. (c) Residual dipolar NH couplings of partially oriented
1D7 (y axis) versus WT ubiquitin (x axis) in DMPC:DHPC bicelles
[16]. WT dipolar couplings were taken from Cornilescu et al.
[25]. The difference in the range of dipolar couplings between
the two samples is due to differences in bicelle content.
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