Figure 1.
Fig. 1. Linear head-to-tail heterodimer of nNOS-syntrophin PDZ
domains. (A) The nNOS PDZ domain (orange) has a polarized
structure with distinct receptor (peptide binding groove) and
ligand ( -finger)
faces. The nNOS ligand face docks against the syntrophin PDZ
domain (purple) peptide binding groove. (B) Structure of the
syntrophin PDZ domain (purple) in complex with a COOH-terminal
peptide (orange) (10). The figure was generated with the program
MOLSCRIPT (25).
The above figure is reprinted
by permission from the AAAs:
Science
(1999,
284,
812-815)
copyright 1999.
-finger)
faces. The nNOS ligand face docks against the syntrophin PDZ
domain (purple) peptide binding groove. (B) Structure of the
syntrophin PDZ domain (purple) in complex with a COOH-terminal
peptide (orange) (10). The figure was generated with the program
MOLSCRIPT (25).