Figure 1 - full size

 

Figure 1.
Figure 1 Electron density for residues at the N-terminus of anionic salmon trypsin in complex with the squash-seed inhibitor CPTI-II. The maps are from simulated annealing where residues 24 and 28 were refined as alanines. The 2F[o] - F[c] map (grey) is contoured at 1.5 and the F[o] - F[c] map (black) is contoured at 3 . Both maps clearly identify residues 24 and 28 as prolines. The coordinates of the final refined model are superimposed on the simulated-annealing maps. The figure was produced using BOBSCRIPT (Kraulis, 1991[Kraulis, P. J. (1991). J. Appl. Cryst. 24, 946-950.]; Esnouf, 1997[Esnouf, R. M. (1997). J. Mol. Graph. 15, 133-138.]).

The above figure is reprinted by permission from the IUCr: Acta Crystallogr D Biol Crystallogr (1999, 55, 139-148) copyright 1999.