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Title
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The squash family of serine proteinase inhibitors. Amino acid sequences and association equilibrium constants of inhibitors from squash, summer squash, zucchini, and cucumber seeds.
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Authors
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M.Wieczorek,
J.Otlewski,
J.Cook,
K.Parks,
J.Leluk,
A.Wilimowska-Pelc,
A.Polanowski,
T.Wilusz,
M.Laskowski.
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Ref.
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Biochem Biophys Res Commun, 1985,
126,
646-652.
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PubMed id
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Abstract
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Six amino acid sequences for trypsin inhibitors isolated from squash, summer
squash, zucchini, and cucumber seeds were determined. All these inhibitors along
with the two previously sequenced squash inhibitors (1) form the squash
inhibitor family. The striking characteristic of the family is that its member
inhibitors are very small (29-32 residues, 3 disulfide bridges). The association
equilibrium constants with bovine beta trypsin for 6 squash family inhibitors
were determined and range from 5.9 X 10(10) to 9.5 X 10(11) M-1.
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