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Title
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Crystallization and preliminary crystallographic studies of an apoptosis-linked calcium-binding protein ALG-2.
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Authors
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F.Wu,
M.Zhang,
W.Gong.
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Ref.
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Acta Crystallogr D Biol Crystallogr, 2001,
57,
1162-1163.
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PubMed id
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Abstract
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ALG-2 is an apoptosis-linked Ca(2+)-binding protein. It is required for T-cell
receptor-induced, Fas-induced and glucocorticoid-induced cell death.
Structurally, ALG-2 contains five putative EF-hand Ca(2+)-binding sites.
Ca(2+)-free ALG-2 was crystallized in two crystal forms by the hanging-drop
vapour-diffusion method.
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