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Pfam domain PF02022

Pfam domain PF02022

Pfam domain:   
  PF02022 - Integrase Zinc binding domain  

Below is the list of protein structures in the PDB containing Pfam domain PF02022.

+/- Key to table

Structures in the PDB containing this domain: 1086

  Pfam domain
architecture
UniProt
accession
UniProt id Protein name PDB structures
1.
Q74085 Q74085_9HIV1 Pol
2opqB.
 
Q5QGH9 Q5QGH9_SIV Pol protein
2samA.
 
Q673V0 Q673V0_9HIV1 Pol protein
3mwsA.
 
Q72498 Q72498_9HIV1 POL polyprotein
3ao1A, 3ao3A, 3ao4A, 3ao5A, 3l3uA, 3l3vA, 3ovnA, 3vq4A, 3vq5A, 3vq6A, 3vq7A, 3vq8A, 3vq9A, 3vqaA, 3vqbA, 3vqcA, 3vqdA, 3vqeA, 3vqpA, 3vqqA.
 
A7YKL0 A7YKL0_9HIV1 Pol protein
3dm2A, 3dmjA, 3dokA, 3dolA.
 
Q74596 Q74596_9HIV1 Pol
3dm2B, 3dmjB.
 
Q88016 Q88016_SIVM3 Pol polyprotein
1sipA.
2.
P11204 POL_EIAV9 Pol polyprotein (E.C. 3.4.23.-, 2.7.7.49, 3.1.26.13, 3.1.13.2)
1ducA, 1dunA.
 
P03371 POL_EIAVY Pol polyprotein (E.C. 3.4.23.-, 2.7.7.49, 3.1.26.13, 3.1.13.2)
1eqiA.
 
P35956 POL_VILVK Pol polyprotein (E.C. 3.4.23.-, 2.7.7.49, 3.1.26.13, 3.1.13.2, 3.6.1.23)
3hpgA, 3hphA.
 
P32542 POL_EIAVC Pol polyprotein (E.C. 3.4.23.-, 2.7.7.49, 3.1.26.13, 3.1.13.2)
1fmbA, 2fmbA.
3.
Q66972 Q66972_9RETR POL protein
2hahA, 4fivA.
 
P16088 POL_FIVPE Pol polyprotein (E.C. 3.4.23.-, 2.7.7.49, 3.1.26.13, 3.1.13.2, 3.6.1.23)
1b11A, 1dutA, 1f7dA, 1f7kA, 1f7nA, 1f7oA, 1f7pA, 1f7qA, 1f7rA, 1fivA, 2fivA, 2hahA, 3fivA, 3ogpA, 3ogqA, 4fivA, 5fivA, 6fivA.
4.
P19560 POL_BIV29 Gag-Pol polyprotein (E.C. 3.4.23.-, 2.7.7.49, 2.7.7.7, 3.1.26.13, 3.1.13.2)
3kkrA, 3kksA.
5.
P12499 POL_HV1Z2 Gag-Pol polyprotein (E.C. 3.4.23.16, 2.7.7.49, 2.7.7.7, 3.1.26.13, 3.1.13.2)
1hxwA, 1proA, 1vijA, 1vikA, 2wl0A, 2xyeA, 2xyfA, 3kf0A, 3kfnA, 3kfpA, 3kfrA, 3kfsA, 4dqbA, 4dqcA, 4dqeA, 4dqfA, 4dqgA, 4dqhA, 4e43A, 4ej8A, 4ejdA, 4ejkA, 4ejlA, 4k4pA, 4k4qA, 4k4rA.
 
P04588 POL_HV1MA Gag-Pol polyprotein (E.C. 3.4.23.16, 2.7.7.49, 2.7.7.7, 3.1.26.13, 3.1.13.2)
3ixoA.
 
P03366 POL_HV1B1 Gag-Pol polyprotein (E.C. 3.4.23.16, 2.7.7.49, 2.7.7.7, 3.1.26.13, 3.1.13.2)
1a9mA, 1ajvA, 1ajxA, 1axaA, 1bqmA, 1bqnA, 1c9rA, 1d4hA, 1d4iA, 1d4jA, 1dloA, 1dw6C, 1ebkC, 1ebwA, 1ebyA, 1ebzA, 1ec0A, 1ec1A, 1ec2A, 1ec3A, 1eetA, 1g35A, 1gnmA, 1gnnA, 1gnoA, 1harA, 1hbvA, 1hefE, 1hegE, 1hihA, 1hmvA, 1hniA, 1hnvA, 1hosA, 1hpsA, 1hpzA, 1hqeA, 1hquA, 1hrhA, 1hteA, 1htfA, 1htgA, 1hviA, 1hvkA, 1hvpA, 1hvuA, 1hysA, 1ikvA, 1ikwA, 1ikxA, 1ikyA, 1j5oA, 1merA, 1mesA, 1metA, 1meuA, 1n5yA, 1n6qA, 1npaA, 1npvA, 1npwA, 1qe1A, 1qmcA, 1r0aA, 1rdhA, 1rtdA, 1rvlA, 1rvmA, 1rvnA, 1rvoA, 1rvpA, 1rvqA, 1rvrA, 1s6pA, 1s6qA, 1s9eA, 1s9gA, 1sbgA, 1suqA, 1sv5A, 1t03A, 1t05A, 1t7kA, 1tv6A, 1tvrA, 1uwbA, 1w5vA, 1w5wA, 1w5xA, 1w5yA, 1yt9A, 1zp8A, 1zpaA, 1zsfA, 1zsrA, 2aquA, 2b5jA, 2b6aA, 2banA, 2bbbA, 2be2A, 2exfA, 2fdeA, 2g69A, 2hb3A, 2hmiA, 2hnzB, 2hs1A, 2hs2A, 2i4dA, 2i4uA, 2i4vA, 2i4wA, 2i4xA, 2i5jB, 2iajA, 2ic3A, 2idwA, 2ieoA, 2jzwA, 2l45A, 2l46A, 2l4lA, 2uxzA, 2uy0A, 2vg5A, 2vg6A, 2vg7A, 2wkzA, 2ykmA, 2yknA, 2zd1A, 2ze2A, 3aviA, 3bgrA, 3dlkA, 3ggaG, 3ggvB, 3ggxA, 3hvtA, 3ig1A, 3irxA, 3is9A, 3isnC, 3ithA, 3jsmA, 3jytA, 3k2pA, 3k4vA, 3kleA, 3klfA, 3klgA, 3klhA, 3kliA, 3ndtA, 3nu3A, 3nu4A, 3nu5A, 3nu6A, 3nu9A, 3nujA, 3nuoA, 3ok9A, 3psuA, 3qaaA, 3qlhA, 3qo9A, 3tkgA, 3tkwA, 3tl9A, 3tlhA, 3v4iA, 3v6dA, 3v81A, 3zpsA, 3zptA, 3zpuA, 4dg1A, 4g1qA, 4h4mA, 4h4oA, 4i2pA, 4i2qA, 4i7gA, 4iclA, 4id5A, 4idkA, 4ifvA, 4ifyA, 4ig0A, 4ig3A, 4je2A, 4kfbA, 4kkoA, 4ko0A, 4lslA, 4lsnA, 4mfbA, 4o44A, 4ojrA, 4pquA, 4puoA, 4pwdA, 4q0bA, 4qagA.
 
P18042 POL_HV2G1 Gag-Pol polyprotein (E.C. 3.4.23.47, 2.7.7.49, 2.7.7.7, 3.1.26.13, 3.1.13.2)
1nc8A, 1v1eA, 2cb7A, 2e1xA, 2iwjA.
 
P05961 POL_HV1MN Gag-Pol polyprotein (E.C. 3.4.23.16, 2.7.7.49, 2.7.7.7, 3.1.26.13, 3.1.13.2)
1aafA.
 
P04587 POL_HV1B5 Gag-Pol polyprotein (E.C. 3.4.23.16, 2.7.7.49, 2.7.7.7, 3.1.26.13, 3.1.13.2)
1bdlA, 1bdqA, 1bdrA, 1fejC, 1ff0C, 1fffC, 1ffiC, 1fg6C, 1fg8C, 1fgcC, 1g2kA, 1hpvA, 1hvjA, 1hvsA, 1k1tA, 1k1uA, 1k2bA, 1k2cA, 1q9pA, 1tcxA, 1wjeA, 1wjfA, 2aocA, 2aodA, 2aoeA, 2aofA, 2aogA, 2aohA, 2aoiA, 2aojA, 2avmA, 2avoA, 2avqA, 2avsA, 2avvA, 2bpvA, 2bpwA, 2bpxA, 2bpyA, 2bpzA, 2f80A, 2f81A, 2f8gA, 2g3lA, 2nmwA, 2nmyA, 2nmzA, 2nnkA, 2nnpA, 2r38A, 2r3tA, 2r3wA, 2z54A, 3b7vA, 3b80A, 3bc4A, 3bgbA, 3bgcA, 3cywA, 3cyxA, 3d1xA, 3d1yA, 3d1zA, 3d20A.
 
O12158 POL_HV192 Gag-Pol polyprotein (E.C. 3.4.23.16, 2.7.7.49, 2.7.7.7, 3.1.26.13, 3.1.13.2)
2r5pA, 2r5qA, 2r8nA.
 
P12497 POL_HV1N5 Gag-Pol polyprotein (E.C. 3.4.23.16, 2.7.7.49, 2.7.7.7, 3.1.26.13, 3.1.13.2)
1a43A, 1a8oA, 1afvA, 1ak4C, 1aumA, 1b92A, 1b9dA, 1b9fA, 1bajA, 1bhlA, 1bi4A, 1bisA, 1biuA, 1bizA, 1bl3A, 1hiwA, 1itgA, 1k6yA, 1m9dC, 1qs4A, 1uphA, 1wjbA, 1wjdA, 1wknA, 1za9A, 2b4jA, 2golA, 2gonA, 2h3fA, 2h3iA, 2h3qA, 2h3vA, 2h3zA, 2hmxA, 2hvpA, 2itgA, 2jprA, 2jygA, 2jylA, 2lf4A, 2lyaA, 2lybA, 2m3zA, 2m8lA, 2m8nA, 2m8pA, 2ontA, 2pwmA, 2pwoA, 2pxrC, 2x2dD, 2xdeA, 2xv6A, 2xxmA, 3av9A, 3avaA, 3avbA, 3avcA, 3avfA, 3avgA, 3avhA, 3avjA, 3avkA, 3avlA, 3avmA, 3avnA, 3dikA, 3dphA, 3ds0A, 3ds1A, 3ds2A, 3ds3A, 3ds4A, 3ds5A, 3dtjA, 3gv2A, 3h47A, 3h4eA, 3lptA, 3lpuA, 3lryA, 3mgeA, 3nf6A, 3nf7A, 3nf8A, 3nf9A, 3nfaA, 3p05A, 3p0aA, 3s85A, 3wneA, 3wnfA, 3wngA, 3wnhA, 4ah9A, 4ahrA, 4ahsA, 4ahtA, 4ahuA, 4ahvA, 4cocA, 4copA, 4dgaC, 4dgeC, 4dmnA, 4e1mA, 4e1nA, 4e91A, 4e92A, 4gvmA, 4gw6A, 4id1A, 4ipyA, 4jlhA, 4jmuA, 4lqwC, 4nx4C, 4o0jA, 4o55A, 4o5bA, 4phvA, 5hvpA, 9hvpA.
 
P04585 POL_HV1H2 Gag-Pol polyprotein (E.C. 3.4.23.16, 2.7.7.49, 2.7.7.7, 3.1.26.13, 3.1.13.2)
1a30A, 1bv7A, 1bv9A, 1bveA, 1bvgA, 1bwaA, 1bwbA, 1c0tA, 1c0uA, 1c1bA, 1c1cA, 1dmpA, 1dtqA, 1dttA, 1ep4A, 1eskA, 1ex4A, 1exqA, 1fb7A, 1fk9A, 1fkoA, 1fkpA, 1g6lA, 1hivA, 1hvhA, 1hvrA, 1hwrA, 1hxbA, 1jkhA, 1jlaA, 1jlbA, 1jlcA, 1jleA, 1jlfA, 1jlgA, 1jlqA, 1klmA, 1lkuA, 1lv1A, 1lw0A, 1lw2A, 1lwcA, 1lweA, 1lwfA, 1ncpN, 1o1wA, 1odwA, 1odxA, 1odyA, 1qbrA, 1qbsA, 1qbtA, 1qbuA, 1revA, 1rt1A, 1rt2A, 1rt3A, 1rt4A, 1rt5A, 1rt6A, 1rt7A, 1rtdB, 1rthA, 1rtiA, 1rtjA, 1s1tA, 1s1uA, 1s1vA, 1s1wA, 1s1xA, 1t05B, 1tamA, 1tktA, 1tkxA, 1tkzA, 1tl1A, 1tl3A, 1vrtA, 1vruA, 2hndA, 2hnyA, 2hnzA, 2kodA, 2nphA, 2oppA, 2opqA, 2oprA, 2opsA, 2rf2A, 2rkiA, 2whhA, 2womA, 2wonA, 2ynfA, 2yngA, 2ynhA, 2yniA, 3ao2A, 3c6tA, 3c6uA, 3di6A, 3dleA, 3dlgA, 3dm2A, 3dmjA, 3dokA, 3dolA, 3doxA, 3drpA, 3drrA, 3drsA, 3dyaA, 3e01A, 3ffiA, 3i0rA, 3i0sA, 3kjvA, 3kk1A, 3kk2A, 3kk3A, 3kt2A, 3kt5A, 3lakA, 3lalA, 3lamA, 3lanA, 3lp0A, 3lp1A, 3lp2A, 3m8pA, 3m8qA, 3mecA, 3medA, 3meeA, 3megA, 3mimA, 3n3iA, 3nbpA, 3phvA, 3qipA, 3t19A, 3t1aA, 3tamA, 4b3oA, 4b3pA, 4b3qA, 4i7fA, 4kseB, 4kv8A, 4ncgA, 4qlhA.
 
P03367 POL_HV1BR Gag-Pol polyprotein (E.C. 3.4.23.16, 2.7.7.49, 2.7.7.7, 3.1.26.13, 3.1.13.2)
1a8gA, 1a8kA, 1a94A, 1aaqA, 1d4sA, 1d4yA, 1dazC, 1difA, 1fqxA, 1hhpA, 1hniB, 1hpoA, 1hpxA, 1hsgA, 1hvlA, 1iiqA, 1iziA, 1lzqA, 1m0bA, 1mrwA, 1mrxA, 1msmA, 1msnA, 1nh0A, 1rl8A, 1s6gA, 1sdtA, 1sduA, 1sdvA, 1sguA, 1sh9A, 1sp5A, 1u8gA, 1upjA, 1xl2A, 1xl5A, 1z8cA, 1zbgA, 1zj7A, 1zlfA, 1zpkA, 1ztzA, 2a1eA, 2az8A, 2az9A, 2azbA, 2azcA, 2b7zB, 2bb9A, 2fndP, 2hb2A, 2hb4A, 2hc0A, 2hndB, 2hnyB, 2ienA, 2o4kA, 2o4lA, 2o4nA, 2o4pA, 2o4sA, 2p3bA, 2pk5A, 2pk6A, 2pqzA, 2pwcA, 2pwrA, 2pymA, 2pynA, 2q63A, 2q64A, 2qakA, 2qciA, 2qd6A, 2qd7A, 2qd8A, 2qhcA, 2qnnA, 2qnpA, 2qnqA, 2r43A, 2upjA, 2z4oA, 2zgaA, 2zyeA, 3a2oA, 3bheA, 3bvaA, 3bvbA, 3cktA, 3djkA, 3dk1A, 3fx5A, 3ggtA, 3gguA, 3h5bA, 3i6oA, 3i8wA, 3jvwA, 3jvyA, 3jw2A, 3kdbA, 3kdcA, 3kddA, 3nduA, 3ndwA, 3ndxA, 3nlsA, 3pwmA, 3pwrA, 3qbfA, 3qihA, 3qn8A, 3qozA, 3qp0A, 3qpjA, 3qrmA, 3qroA, 3qrsA, 3st5A, 3t11A, 3t3cA, 3tofA, 3togA, 3tohA, 3ttpA, 3ucbA, 3uf3A, 3ufnA, 3uhlA, 3vf5A, 3vf7A, 3vfbA, 4dfgA, 4fafA, 4fe6A, 4fl8A, 4flgB, 4fm6B, 4gb2A, 4hdbA, 4hdfB, 4hdpB, 4he9A, 4hegB, 4hlaA, 4j54A, 4j55A, 4j5jA, 4jecA, 7upjA.
 
P03369 POL_HV1A2 Gag-Pol polyprotein (E.C. 3.4.23.16, 2.7.7.49, 2.7.7.7, 3.1.26.13, 3.1.13.2)
1aidA, 1b6jA, 1b6kA, 1b6lA, 1b6mA, 1b6nA, 1b6oA, 1b6pA, 1cpiA, 1d4kA, 1d4lA, 1f7aA, 1kj4A, 1kj7A, 1kjfA, 1kjgA, 1kjhA, 1kzkA, 1mt7A, 1mt8A, 1mt9A, 1mtbA, 1mtrA, 1n49A, 1t3rA, 1tsqA, 1tsuA, 1ytgA, 1ythA, 1z1hA, 1z1rA, 2aidA, 2f3kA, 2fguA, 2fgvA, 2fnsA, 2fntA, 2j9jA, 2j9kA, 2je4A, 2nxdA, 2nxlA, 2nxmA, 2q3kA, 2qhyA, 2qhzA, 2qi0A, 2qi1A, 2qi3A, 2qi4A, 2qi5A, 2qi6A, 2qi7A, 3aidA, 3bxrA, 3bxsA, 3ekpA, 3ekqA, 3ektA, 3ekvA, 3ekwA, 3ekxA, 3ekyA, 3el0A, 3el1A, 3el4A, 3el5A, 3el9A, 3em3A, 3em4A, 3em6A, 3fsmA, 3gi0A, 3gi4A, 3gi5A, 3gi6A, 3hauA, 3hawA, 3hboA, 3hdkA, 3hloA, 3hvpA, 3i7eA, 3iawA, 3ka2A, 3lzvA, 3mxdA, 3mxeA, 3nwqA, 3nwxA, 3nxnA, 3nygA, 3o9fA, 3o9gA, 3o9hA, 3o9iA, 3oxvB, 3oxwA, 3oxxA, 3oy4A, 3r4bA, 4ep2A, 4ep3A, 4epjA, 4eq0A, 4eqjA, 4f73A, 4f74A, 4f75A, 4f76A, 4hvpA, 7hvpA, 8hvpA.
 
P05896 POL_SIVM1 Gag-Pol polyprotein (E.C. 3.4.23.16, 2.7.7.49, 2.7.7.7, 3.1.26.13, 3.1.13.2)
1az5A, 1c6vA, 1sivA, 1tcwA, 1ytiA, 1ytjA.
 
P24740 POL_HV1U4 Gag-Pol polyprotein (E.C. 3.4.23.16, 2.7.7.49, 2.7.7.7, 3.1.26.13, 3.1.13.2)
1ncpC, 3lzsA, 3lzuB.
 
P05897 POL_SIVMK Gag-Pol polyprotein (E.C. 3.4.23.16, 2.7.7.49, 2.7.7.7, 3.1.26.13, 3.1.13.2)
1c6vX, 1ecwA, 1ed1A.
 
P05959 POL_HV1RH Gag-Pol polyprotein (E.C. 3.4.23.16, 2.7.7.49, 2.7.7.7, 3.1.26.13, 3.1.13.2)
2fxeA.
 
P35963 POL_HV1Y2 Gag-Pol polyprotein (E.C. 3.4.23.16, 2.7.7.49, 2.7.7.7, 3.1.26.13, 3.1.13.2)
1f6uA, 1k6cA, 1k6pA, 1k6tA, 1k6vA, 1mfsA, 1t7iA, 1t7jA, 1wjaA, 1wjcA, 2jo0A, 2k1cA, 2l6eA, 3oq7A, 3oqaA, 3oqdA, 3otsA, 3otyA, 3ou1A, 3ou3A, 3ou4A, 3ouaA, 3oubA, 3oucA, 3oudA, 3pj6A, 3u7sA, 4a6bA, 4a6cA.
 
P04584 POL_HV2RO Gag-Pol polyprotein (E.C. 3.4.23.47, 2.7.7.49, 2.7.7.7, 3.1.26.13, 3.1.13.2)
1e0eA, 1hiiA, 1hshA, 1hsiA, 1idaA, 1idbA, 1ivpA, 1ivqA, 1jldA, 1mu2A, 1phvA, 2hpeA, 2hpfA, 2k4eA, 2k4hA, 2k4iA, 2mipA, 2phvA, 3ebzA, 3ec0A, 3ecgA, 3f9kA, 3upjA, 4upjA, 5upjA, 6upjA.
 
Q90VT5 Q90VT5_9HIV1 Gag-Pol fusion polyprotein
3d3tA.
 
P0C6F2 POL_HV1LW Gag-Pol polyprotein (E.C. 3.4.23.16, 2.7.7.49, 2.7.7.7, 3.1.26.13, 3.1.13.2)
3lp3A, 3th9A, 3vfaA, 4i8wA, 4i8zA, 4mc1A, 4mc2A, 4mc6A, 4mc9A, 4nyfA, 4qgiA.
6.
P03363 POL_HTLV2 Gag-Pro-Pol polyprotein (E.C. 3.4.23.-, 2.7.7.49, 2.7.7.7, 3.1.26.4)
1jvrA.
7.
Q70XD7 Q70XD7_9HIV1 Gag-pol fusion polyprotein
2ypkC, 2yplC.
8.
Q76353 Q76353_9HIV1 Integrase
1hyvA, 1hyzA, 3zcmA, 3zsoA, 3zsqA, 3zsrA, 3zsvA, 3zswA, 3zsxA, 3zsyA, 3zszA, 3zt0A, 3zt1A, 3zt2A, 3zt3A, 3zt4A, 4ce9A, 4ceaA, 4cebA, 4cecA, 4cedA, 4ceeA, 4cefA, 4ceoA, 4ceqA, 4cerA, 4cesA, 4cezA, 4cf0A, 4cf1A, 4cf2A, 4cf8A, 4cf9A, 4cfaA, 4cfbA, 4cfcA, 4cfdA, 4cgdA, 4cgfA, 4cggA, 4cghA, 4cgiA, 4cgjA, 4chnA, 4choA, 4chpA, 4chqA, 4chyA, 4chzA, 4cieA, 4cifA, 4cigA, 4cj3A, 4cj4A, 4cj5A, 4cjeA, 4cjfA, 4cjkA, 4cjlA, 4cjpA, 4cjqA, 4cjrA, 4cjsA, 4cjtA, 4cjuA, 4cjvA, 4cjwA, 4ck1A, 4ck2A, 4ck3A, 4lh4A, 4lh5A, 4ovlA.
9.
P03362 POL_HTL1A Gag-Pro-Pol polyprotein (E.C. 3.4.23.-, 2.7.7.49, 2.7.7.7, 3.1.26.4)
1qrjA, 2b7fA.
10.
P03354 POL_RSVP Gag-Pro-Pol polyprotein (E.C. 3.4.23.-, 2.7.7.49, 2.7.7.7, 3.1.26.4, 2.7.7.49, 2.7.7.7, 3.1.26.4)
1c0mA, 1c1aA, 3tirA, 4fw1A, 4fw2A.
 
O92956 POL_RSVSB Gag-Pro-Pol polyprotein (E.C. 3.4.23.-, 2.7.7.49, 2.7.7.7, 3.1.26.4, 2.7.7.49, 2.7.7.7, 3.1.26.4)
1a5vA, 1a5wA, 1a5xA, 1asuA, 1asvA, 1aswA, 1cxqA, 1cxuA, 1cz9A, 1czbA, 1vsdA, 1vseA, 1vsfA, 1vshA, 1vsiA, 1vsjA, 1vskA, 1vslA, 1vsmA, 3o4nA, 3o4qA.

List of Pfam domains

  Pfam code Pfam id Description
PF02022 Integrase_Zn Integrase Zinc binding domain
PF00075 RNase_H RNase H
PF00077 RVP Retroviral aspartyl protease
PF00078 RVT_1 Reverse transcriptase (RNA-dependent DNA polymerase)
PF00098 zf-CCHC Zinc knuckle
PF00540 Gag_p17 gag gene protein p17 (matrix protein)
PF00552 IN_DBD_C Integrase DNA binding domain
PF00607 Gag_p24 gag gene protein p24 (core nucleocapsid protein)
PF00665 rve Integrase core domain
PF00692 dUTPase dUTPase
PF02228 Gag_p19 Major core protein p19
PF02813 Retro_M Retroviral M domain
PF06815 RVT_connect Reverse transcriptase connection domain
PF06817 RVT_thumb Reverse transcriptase thumb domain
PF08705 Gag_p6 Gag protein p6
PB133292

 

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