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Pfam domain PF00439

Pfam domain PF00439

Pfam domain:   
  PF00439 - Bromodomain  

Below is the list of protein structures in the PDB containing Pfam domain PF00439.

+/- Key to table

Structures in the PDB containing this domain: 367

  Pfam domain
architecture
UniProt
accession
UniProt id Protein name PDB structures
1.
Q8IK82 Q8IK82_PLAF7 Bromodomain protein, putative {ECO:0000313|EMBL:AAN37337.1}
4nxjA.
 
Q8N9Q1 Q8N9Q1_HUMAN cDNA FLJ36757 fis, clone UTERU2018522, highly similar to Human transcriptional activator hSNF2a {ECO:0000313|EMBL:BAC04280.1}
4qy4A.
2.
Q15059 BRD3_HUMAN Bromodomain-containing protein 3
2e7nA, 2nxbA, 2oo1A, 2yw5A, 3s91A, 3s92A.
 
Q8K2F0 BRD3_MOUSE Bromodomain-containing protein 3
2l5eA.
3.
Q27198 Q27198_TETTH HAT A1 {ECO:0000313|EMBL:AAB01099.1}
1m1dA, 1pu9A, 1puaA, 1q2cA, 1q2dA, 1qsnA, 1qsrA, 1qstA, 5gcnA.
 
Q5CUE2 Q5CUE2_CRYPI GCN5 like acetylase + bromodomain {ECO:0000313|EMBL:EAK89017.1}
4ldfA.
 
Q03330 GCN5_YEAST Histone acetyltransferase GCN5 (E.C. 2.3.1.48)
1e6iA, 1yghA.
4.
H0Y4R8 H0Y4R8_HUMAN Nuclear autoantigen Sp-100 {ECO:0000313|Ensembl:ENSP00000393679}
4ptbA.
5.
Q58F21 BRDT_HUMAN Bromodomain testis-specific protein
2rfjA, 4flpA, 4kcxA.
6.
Q02206 RSC4_YEAST Chromatin structure-remodeling complex subunit RSC4
2r0sA, 2r0vA, 2r0yA, 2r10A.
7.
Q9H8M2 BRD9_HUMAN Bromodomain-containing protein 9
3hmeA.
8.
Q8IJ72 Q8IJ72_PLAF7 Bromodomain protein, putative {ECO:0000313|EMBL:AAN35525.1}
3fkmX.
9.
Q9BXF3 CECR2_HUMAN Cat eye syndrome critical region protein 2
3nxbA.
10.
Q9NPI1 BRD7_HUMAN Bromodomain-containing protein 7
2i7kA.
11.
Q9ULI0 ATD2B_HUMAN ATPase family AAA domain-containing protein 2B (E.C. 3.6.1.3)
2dkwA, 3lxjA.
12.
P25440 BRD2_HUMAN Bromodomain-containing protein 2
1x0jA, 2dvrC, 2dvsA, 2dvvA, 2e3kA, 2g4aA, 2ydwA, 2yekA, 3aqaA, 3oniA, 4a9eA, 4a9fA, 4a9hA, 4a9iA, 4a9jA, 4a9mA, 4a9nA, 4a9oA, 4a9pA, 4aknA, 4algA, 4alhA, 4j1pA, 4mr5A, 4mr6A, 4qeuA, 4qevA, 4qewA, 4uyfA, 4uygA, 4uyhA.
13.
Q15326 ZMY11_HUMAN Zinc finger MYND domain-containing protein 11
4ns5A.
 
Q8R5C8 ZMY11_MOUSE Zinc finger MYND domain-containing protein 11
4n4gA, 4n4hA, 4n4iA.
14.
Q92830 KAT2A_HUMAN Histone acetyltransferase KAT2A (E.C. 2.3.1.48)
1f68A, 1z4rA, 3d7cA.
15.
Q06488 RSC2_YEAST Chromatin structure-remodeling complex subunit RSC2
4bb7A.
16.
Q92831 KAT2B_HUMAN Histone acetyltransferase KAT2B (E.C. 2.3.1.48)
1cm0B, 1jm4B, 1n72A, 1wugA, 1wumA, 1zs5A, 2rnwA, 2rnxA, 3gg3A, 4nsqA.
17.
Q13342 SP140_HUMAN Nuclear body protein SP140 {ECO:0000312|HGNC:HGNC:17133}
2md7B, 2md8C.
18.
Q6PL18 ATAD2_HUMAN ATPase family AAA domain-containing protein 2 (E.C. 3.6.1.3)
3daiA, 4qspA, 4qsqA, 4qsrA, 4qssA, 4qstA, 4qsuA, 4qsvA, 4qswA, 4qsxA, 4qutA, 4quuA, 4tt2A, 4tt4A, 4tt6A, 4tteA, 4tu4A, 4tu6A, 4tylA, 4tz2A, 4tz8A.
19.
Q91Y44 BRDT_MOUSE Bromodomain testis-specific protein
2wp1A, 2wp2A.
20.
Q8IB67 Q8IB67_PLAF7 Histone acetyltransferase GCN5, putative {ECO:0000313|EMBL:CAD51140.2}
4qnsA.
21.
Q9ULU4 PKCB1_HUMAN Protein kinase C-binding protein 1
4cosA.
22.
P55201 BRPF1_HUMAN Peregrin
2d9eA, 2rs9B, 2x35A, 2x4wA, 2x4xA, 2x4yA, 3l42A, 3mo8A, 4lc2A, 4qydA, 4qylA, 4uyeA.
 
O95696 BRD1_HUMAN Bromodomain-containing protein 1
2ku3A, 2l43A, 2lq6A, 3lyiA, 3rcwA.
23.
O15164 TIF1A_HUMAN Transcription intermediary factor 1-alpha (E.C. 6.3.2.-)
2yynA, 3o33A, 3o34A, 3o35A, 3o36A, 3o37A.
24.
P21675 TAF1_HUMAN Transcription initiation factor TFIID subunit 1 (E.C. 2.3.1.48, 2.7.11.1)
1eqfA, 3aadA, 3uv4A, 3uv5A, 4rgwA.
 
Q8IZX4 TAF1L_HUMAN Transcription initiation factor TFIID subunit 1-like
3hmhA.
25.
P51123 TAF1_DROME Transcription initiation factor TFIID subunit 1 (E.C. 2.7.11.1)
1tbaA.
26.
Q9ULD4 BRPF3_HUMAN Bromodomain and PHD finger-containing protein 3
3pfsA.
27.
Q9UIG0 BAZ1B_HUMAN Tyrosine-protein kinase BAZ1B (E.C. 2.7.10.2)
1f62A.
28.
P51532 SMCA4_HUMAN Transcription activator BRG1 (E.C. 3.6.4.-)
2grcA, 2h60A, 3uvdA.
29.
P22082 SNF2_YEAST Transcription regulatory protein SNF2 (E.C. 3.6.4.-)
4i6mC.
30.
O60885 BRD4_HUMAN Bromodomain-containing protein 4
2i8nA, 2lspB, 2mjvB, 2ossA, 2ouoA, 2yelA, 2yemA, 3mxfA, 3p5oA, 3svfA, 3svgA, 3u5jA, 3u5kA, 3u5lA, 3uvwA, 3uvxA, 3uvyA, 3uw9A, 3zyuA, 4a9lA, 4bjxA, 4bw1A, 4bw2A, 4bw3A, 4bw4A, 4c66A, 4c67A, 4cfkA, 4cflA, 4cl9A, 4clbA, 4donA, 4e96A, 4f3iA, 4gpjA, 4hbvA, 4hbwA, 4hbxA, 4hbyA, 4hxkA, 4hxlA, 4hxmA, 4hxnA, 4hxoA, 4hxpA, 4hxrA, 4hxsA, 4iooA, 4ioqA, 4iorA, 4j0rA, 4j0sA, 4j3iA, 4kv1A, 4kv4A, 4lr6A, 4lrgA, 4lyiA, 4lysA, 4lywA, 4lzrA, 4lzsA, 4menA, 4meoA, 4mepA, 4meqA, 4mr3A, 4mr4A, 4nr8A, 4nucA, 4nudA, 4nueA, 4o70A, 4o71A, 4o72A, 4o73A, 4o74A, 4o75A, 4o76A, 4o77A, 4o78A, 4o7aA, 4o7bA, 4o7cA, 4o7eA, 4o7fA, 4ogiA, 4ogjA, 4pceA, 4pciA, 4ps5A, 4qzsA, 4uydA, 4wivA.
31.
Q9UPN9 TRI33_HUMAN E3 ubiquitin-protein ligase TRIM33 (E.C. 6.3.2.-)
3u5mA, 3u5nA, 3u5oA, 3u5pA.
32.
Q12830 BPTF_HUMAN Nucleosome-remodeling factor subunit BPTF
2f6jA, 2f6nA, 2fsaA, 2fuiA, 2fuuA, 2ri7A, 3qzsA, 3qztA, 3qzvA, 3uv2A.
33.
Q9ESU6 BRD4_MOUSE Bromodomain-containing protein 4
2dwwA, 2jnsA, 3jvjA, 3jvkA, 3jvlA, 3jvmA, 3mukA, 3mulA.
34.
Q9NR48 ASH1L_HUMAN Histone-lysine N-methyltransferase ASH1L (E.C. 2.1.1.43)
3mqmA, 3opeA.
35.
Q8WWQ0 PHIP_HUMAN PH-interacting protein
3mb3A.
36.
P51531 SMCA2_HUMAN Probable global transcription activator SNF2L2 (E.C. 3.6.4.-)
2datA.
37.
P45481 CBP_MOUSE CREB-binding protein (E.C. 2.3.1.48 {ECO:0000250|UniProtKB:Q92793})
1f81A, 1jjsA, 1kbhB, 1kdxA, 1l8cA, 1r8uB, 1sb0A, 1totA, 1u2nA, 2aghB, 2c52A, 2ka4A, 2ka6A, 2kkjA, 2l14A, 2lqhA, 2lqiA, 2lwwA, 4i9oA.
38.
Q90941 PB1_CHICK Protein polybromo-1
1w4sA.
 
Q86U86 PB1_HUMAN Protein polybromo-1
2ktbB, 3g0jA, 3hmfA, 3iu5A, 3iu6A, 3k2jA, 3ljwA, 3mb4A, 3tlpA, 4q0nA, 4q0oA.
 
Q8BSQ9 PB1_MOUSE Protein polybromo-1
2yqdA.
39.
Q9UIF8 BAZ2B_HUMAN Bromodomain adjacent to zinc finger domain protein 2B
2e7oA, 3g0lA, 3q2fA, 4cupA, 4cuqA, 4curA, 4cusA, 4cutA, 4cuuA, 4ir3A, 4ir4A, 4ir5A, 4ir6A, 4nr9A, 4nraA, 4nrbA, 4nrcA, 4qc1A, 4qc3A, 4qf3A, 4rvrA.
40.
Q09472 EP300_HUMAN Histone acetyltransferase p300 (E.C. 2.3.1.48 {ECO:0000269|PubMed:23415232, ECO:0000269|PubMed:23934153, ECO:0000269|PubMed:8945521})
1l3eB, 1p4qB, 2k8fA, 2mh0B, 3biyA, 3i3jA, 3io2A, 3p57P, 3t92A, 4bhwA, 4pzrA, 4pzsA, 4pztA.
41.
Q92793 CBP_HUMAN CREB-binding protein (E.C. 2.3.1.48 {ECO:0000269|PubMed:24616510})
1jspB, 1liqA, 1wo3A, 1wo4A, 1wo5A, 1wo6A, 1wo7A, 1zoqC, 2d82A, 2kjeA, 2kwfA, 2l84A, 2l85A, 2lxsA, 2lxtA, 2rnyA, 3dwyA, 3p1cA, 3p1dA, 3p1eA, 3p1fA, 3svhA, 4a9kA, 4n3wA, 4n4fA, 4nyvA, 4nywA, 4nyxA, 4oufA.
42.
Q9NSI6 BRWD1_HUMAN Bromodomain and WD repeat-containing protein 1
3q2eA.
43.
Q9UIF9 BAZ2A_HUMAN Bromodomain adjacent to zinc finger domain protein 2A
4lz2A, 4q6fA, 4qbmA, 4qf2A.

List of Pfam domains

  Pfam code Pfam id Description
PF00439 Bromodomain Bromodomain
PF00004 AAA ATPase family associated with various cellular activities (AAA)
PF00176 SNF2_N SNF2 family N-terminal domain
PF00271 Helicase_C Helicase conserved C-terminal domain
PF00400 WD40 WD domain, G-beta repeat
PF00505 HMG_box HMG (high mobility group) box
PF00569 ZZ Zinc finger, ZZ type
PF00583 Acetyltransf_1 Acetyltransferase (GNAT) family
PF00628 PHD PHD-finger
PF00643 zf-B_box B-box zinc finger
PF00855 PWWP PWWP domain
PF00856 SET SET domain
PF01342 SAND SAND domain
PF01426 BAH BAH domain
PF01429 MBD Methyl-CpG binding domain
PF01753 zf-MYND MYND finger
PF02135 zf-TAZ TAZ zinc finger
PF02172 KIX KIX domain
PF02791 DDT DDT domain
PF03172 Sp100 Sp100 domain
PF06001 DUF902 Domain of Unknown Function (DUF902)
PF06466 PCAF_N PCAF (P300/CBP-associated factor) N-terminal domain
PF07529 HSA HSA
PF07533 BRK BRK domain
PF08214 KAT11 Histone acetylation protein
PF08880 QLQ QLQ
PF09030 Creb_binding Creb binding
PF09247 TBP-binding TATA box-binding protein binding
PF10513 EPL1 Enhancer of polycomb-like
PF10537 WAC_Acf1_DNA_bd ATP-utilising chromatin assembly and remodelling N-terminal
PF12024 DUF3512 Domain of unknown function (DUF3512)
PF12064 DUF3544 Domain of unknown function (DUF3544)
PF12157 DUF3591 Protein of unknown function (DUF3591)
PF12796 Ank_2 Ankyrin repeats (3 copies)
PF13508 Acetyltransf_7 Acetyltransferase (GNAT) domain
PF13639 zf-RING_2 Ring finger domain
PF13831 PHD_2 PHD-finger
PF13832 zf-HC5HC2H_2 PHD-zinc-finger like domain
PF14619 SnAC Snf2-ATP coupling, chromatin remodelling complex
PF15288 zf-CCHC_6 Zinc knuckle
PF15612 WHIM1 WSTF, HB1, Itc1p, MBD9 motif 1
PF15613 WHIM2 WSTF, HB1, Itc1p, MBD9 motif 2
PF15614 WHIM3 WSTF, HB1, Itc1p, MBD9 motif 3
PB000071
PB000361
PB000817
PB000911
PB001543
PB001587
PB001702
PB002366
PB002669
PB002675
PB002929
PB003124
PB004663
PB004946
PB005324
PB005327
PB006310
PB006347
PB006766
PB007883
PB008184
PB008260
PB008532
PB009375
PB010350
PB010717
PB010720
PB010963
PB011064
PB011430
PB011449
PB011628
PB012038
PB012618
PB013010
PB013066
PB014139
PB014208
PB014213
PB014336
PB014861
PB014896
PB015118
PB015526
PB015784
PB017078
PB017427
PB017897
PB018245
PB018246
PB018611
PB018728
PB018973
PB020164
PB022078
PB023116
PB024632
PB025586
PB025722
PB026081
PB027858
PB029595
PB032186
PB035798
PB040477
PB042091
PB055563
PB060538
PB063683
PB064177
PB082408
PB094218
PB106700
PB130965
PB179944
PB358817
PB466356

 

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