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Pfam domain PF00400

Pfam domain PF00400

Pfam domain:   
  PF00400 - WD domain, G-beta repeat  

Below is the list of protein structures in the PDB containing Pfam domain PF00400.

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Structures in the PDB containing this domain: 365

  Pfam domain
architecture
UniProt
accession
UniProt id Protein name PDB structures
1.
Q03774 TRM82_YEAST tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit TRM82
2vduB.
 
Q5T6F0 DCA12_HUMAN DDB1- and CUL4-associated factor 12
3i7pB.
2.
P11655 SEC12_YEAST Guanine nucleotide-exchange factor SEC12
4h5iA, 4h5jA.
3.
P40960 PAC11_YEAST WD repeat-containing protein PAC11
4ht6B.
4.
O36030 YEKI_SCHPO Uncharacterized WD repeat-containing protein C4F10.18
4fhlA, 4fhmA, 4fhnA, 4gq1A, 4gq2P.
5.
Q2YDS1 DDB2_DANRE DNA damage-binding protein 2
3ei1B, 3ei2B, 3ei3B, 4a08B, 4a09B, 4a0aB, 4a0bB, 4a0kD, 4a0lB.
 
Q96MX6 WDR92_HUMAN WD repeat-containing protein 92
3i2nA.
 
Q6CN23 HSV2_KLULA SVP1-like protein 2
4av8A, 4av9A, 4exvA.
 
P78774 ARPC1_SCHPO Actin-related protein 2/3 complex subunit 1
3dwlC.
 
P26449 BUB3_YEAST Cell cycle arrest protein BUB3
1u4cA, 1yfqA, 2i3sA, 2i3tA, 4bl0A.
 
Q58CQ2 ARC1B_BOVIN Actin-related protein 2/3 complex subunit 1B
1k8kC, 1tyqC, 1u2vC, 2p9iC, 2p9kC, 2p9lC, 2p9nC, 2p9pC, 2p9sC, 2p9uC, 3dxkC, 3dxmC, 3rseC, 3ukrC, 3ukuC, 3uleC, 4jd2C.
 
P53196 RPN14_YEAST 26S proteasome regulatory subunit RPN14
3acpA, 3vl1A.
6.
Q24246 DYIN_DROME Cytoplasmic dynein 1 intermediate chain
3fm7C, 3l9kW.
7.
Q8WV16 DCAF4_HUMAN DDB1- and CUL4-associated factor 4
3i8cB.
8.
Q8NFH3 NUP43_HUMAN Nucleoporin Nup43
4i79A.
9.
Q62871 DC1I2_RAT Cytoplasmic dynein 1 intermediate chain 2
2pg1I.
10.
Q06078 UTP21_YEAST U3 small nucleolar RNA-associated protein 21
4nsxA.
11.
Q5TAQ9 DCAF8_HUMAN DDB1- and CUL4-associated factor 8
3i8eC.
12.
O74910 RAF1_SCHPO Rik1-associated factor 1
4o9dB.
13.
Q8I402 Q8I402_PLAF7 Cyclophilin, putative (E.C. 5.2.1.8)
2fu0A.
14.
Q6NUD0 MEP50_XENLA Methylosome protein 50
4g56B.
 
Q02793 SKI8_YEAST Antiviral protein SKI8
1s4uX, 1sq9A, 4bujC.
 
Q92466 DDB2_HUMAN DNA damage-binding protein 2
3ei4B, 3i7lB, 4e54B, 4e5zB.
15.
P39984 HAT2_YEAST Histone acetyltransferase type B subunit 2
4pswB, 4psxB.
16.
Q921E6 EED_MOUSE Polycomb protein EED
2qxvA.
 
O75530 EED_HUMAN Polycomb protein EED
3iiwA, 3iiyA, 3ij0A, 3ij1A, 3ijcA, 3jpxA, 3jzgA, 3jzhA, 3jznA, 3k26A, 3k27A.
17.
Q12834 CDC20_HUMAN Cell division cycle protein 20 homolog
4ggaA, 4ggcA, 4ggdA, 4n14A.
18.
Q9BQA1 MEP50_HUMAN Methylosome protein 50
4gqbB.
19.
P78972 SLP1_SCHPO WD repeat-containing protein slp1
4aezA.
20.
Q96BP3 PPWD1_HUMAN Peptidylprolyl isomerase domain and WD repeat-containing protein 1 (E.C. 5.2.1.8)
2a2nA.
21.
P40217 EIF3I_YEAST Eukaryotic translation initiation factor 3 subunit I
3zwlB.
 
A6ZMK5 EIF3I_YEAS7 Eukaryotic translation initiation factor 3 subunit I
4u1eI.
 
Q96JK2 DCAF5_HUMAN DDB1- and CUL4-associated factor 5
3i89B.
 
P78406 RAE1L_HUMAN mRNA export factor
3mmyA, 4owrA.
 
Q8IMG2 Q8IMG2_DROME CstF-50, isoform B
2xz2A.
22.
P38968 SEC31_YEAST Protein transport protein SEC31
2pm6A, 2pm7A, 2pm9A, 2qtvD, 3mzlB, 4bzjA, 4bzkA.
23.
P38262 SIF2_YEAST SIR4-interacting protein SIF2
1r5mA.
24.
Q5Y1E7 Q5Y1E7_TOXGO Coronin
4ozuA.
25.
Q6P1M3 L2GL2_HUMAN Lethal(2) giant larvae protein homolog 2
3wp0B, 3wp1A.
26.
P53197 CDH1_YEAST APC/C activator protein CDH1
4bh6A.
27.
P39108 PEX7_YEAST Peroxisomal targeting signal 2 receptor
3w15A.
28.
Q13216 ERCC8_HUMAN DNA excision repair protein ERCC-8
4a11B.
 
Q04491 SEC13_YEAST Protein transport protein SEC13
2pm6B, 2pm7B, 2pm9B, 3ikoA, 3jroA, 3jrpA, 3mzkA, 3mzlA, 4bzjB, 4bzkB.
 
Q24D42 Q24D42_TETTS Receptor of activated kinase C 1A, component of 40S small ribosomal subunit
2xzmR, 2xznR.
 
O43818 U3IP2_HUMAN U3 small nucleolar RNA-interacting protein 2
4jxmA.
 
E6PBV0 E6PBV0_TETTH 40S ribosomal protein RACK1
4bpeR, 4bpnR, 4bpoR, 4bppR.
 
Q9BVC4 LST8_HUMAN Target of rapamycin complex subunit LST8
4jsnD, 4jspD, 4jsvD, 4jsxD, 4jt5D, 4jt6D.
 
Q9GZS3 WDR61_HUMAN WD repeat-containing protein 61
3ow8A.
 
P53011 SEH1_YEAST Nucleoporin SEH1
3eweA, 3f3fA, 3f3gA, 3f3pA.
29.
Q13033 STRN3_HUMAN Striatin-3
4n6jA.
30.
O89053 COR1A_MOUSE Coronin-1A
2akfA, 2aq5A, 2b4eA.
31.
Q58WW2 DCAF6_HUMAN DDB1- and CUL4-associated factor 6
3i7oB.
32.
Q9WU70 STXB5_RAT Syntaxin-binding protein 5
1urqA.
33.
P46680 AIP1_YEAST Actin-interacting protein 1
1pguA, 1pi6A.
34.
P36130 CAF4_YEAST CCR4-associated factor 4
2pqrC.
35.
P18851 GBB_YEAST Guanine nucleotide-binding protein subunit beta
1scgB.
36.
P41811 COPB2_YEAST Coatomer subunit beta'
2ynnA, 2ynoA, 2ynpA, 4j73A, 4j77A, 4j78A, 4j79A, 4j81A, 4j82A, 4j84A, 4j86A.
 
A6ZU46 A6ZU46_YEAS7 Coatomer beta'-subunit
3mkqA.
37.
O75717 WDHD1_HUMAN WD repeat and HMG-box DNA-binding protein 1
2d7lA.
38.
P53024 SEC13_PICPG Protein transport protein SEC13
4l9oA.
 
P55735 SEC13_HUMAN Protein SEC13 homolog
3bg0A, 3bg1A.
 
Q383E1 Q383E1_TRYB2 Guanine nucleotide-binding protein beta subunit-like protein
3zey7.
 
P38011 GBLP_YEAST Guanine nucleotide-binding protein subunit beta-like protein
1trjA, 1vw9h, 1vwvh, 1vxvs, 1vxys, 3frxA, 3izba, 3o2zT, 3o30T, 3rfgA, 3rfhA, 3u5cg, 3u5gg, 4byl6, 4byt6, 4cuyg.
 
Q05583 CIAO1_YEAST Cytosolic iron-sulfur protein assembly protein 1
2hesX.
39.
O00423 EMAL1_HUMAN Echinoderm microtubule-associated protein-like 1
4ci8A.
40.
Q8SQS4 TAF5_ENCCU Transcription initiation factor TFIID subunit 5
2j4bA.
41.
Q24572 CAF1_DROME Probable histone-binding protein Caf1
2xyiA, 2yb8B, 2ybaA, 3c99A, 3c9cA.
 
Q09028 RBBP4_HUMAN Histone-binding protein RBBP4
2xu7A, 3gfcA, 4pbyA, 4pbzA, 4pc0A.
 
Q16576 RBBP7_HUMAN Histone-binding protein RBBP7
3cfsB, 3cfvB.
42.
Q676U5 A16L1_HUMAN Autophagy-related protein 16-1
4gdkC, 4gdlC, 4nawC.
43.
P62871 GBB1_BOVIN Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
1a0rB, 1b9xA, 1b9yA, 1gg2B, 1gotB, 1gp2B, 1omwB, 1tbgA, 1xhmA, 2bcjB, 2trcB, 3ah8B, 3cikB, 3krwB, 3krxB, 3pscB, 3pvuB, 3pvwB, 3uzsB, 3v5wB, 4mk0B.
 
P61965 WDR5_MOUSE WD repeat-containing protein 5
2xl2A, 2xl3A.
 
P61964 WDR5_HUMAN WD repeat-containing protein 5
2cnxA, 2co0A, 2g99A, 2g9aA, 2gnqA, 2h13A, 2h14A, 2h68A, 2h6kA, 2h6nA, 2h6qA, 2h9lA, 2h9mA, 2h9nA, 2h9oA, 2h9pA, 2o9kA, 3eg6A, 3emhA, 3mxxA, 3n0dA, 3n0eA, 3p4fA, 3pslA, 3smrA, 3ur4A, 3uvkA, 3uvlA, 3uvmA, 3uvnA, 3uvoA, 4a7jA, 4cy1A, 4cy2A, 4erqA, 4eryA, 4erzA, 4es0A, 4esgA, 4ewrA, 4gm3A, 4gm8A, 4gm9A, 4gmbA, 4ia9A, 4o45A.
 
O76071 CIAO1_HUMAN Probable cytosolic iron-sulfur protein assembly protein CIAO1
3fm0A.
 
F1PLR0 F1PLR0_CANFA Uncharacterized protein
2zkqa.
 
P63244 GBLP_HUMAN Guanine nucleotide-binding protein subunit beta-2-like 1
3j3ag, 4aowA.
 
P62873 GBB1_HUMAN Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
2qnsA, 3kj5A, 4kfmB.
 
G1SJB4 G1SJB4_RABIT Uncharacterized protein
4kzxg, 4kzyg, 4kzzg.
 
P54311 GBB1_RAT Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
3sn6B.
 
O24456 GBLPA_ARATH Guanine nucleotide-binding protein subunit beta-like protein A
3dm0A.
 
O18640 GBLP_DROME Guanine nucleotide-binding protein subunit beta-like protein
3j38g.
 
P63246 GBLP_PIG Guanine nucleotide-binding protein subunit beta-2-like 1
1vx2g, 1vx5g, 4w23g, 4w28g.
 
Q498M4 WDR5_RAT WD repeat-containing protein 5
4qqeA.
44.
P53622 COPA_YEAST Coatomer subunit alpha
3mkqB, 3mv2A, 3mv3A.
45.
P36037 DOA1_YEAST Protein DOA1
3gaeA, 3l3fX, 3odtA, 3pspA, 3pstA.
46.
Q04724 TLE1_HUMAN Transducin-like enhancer protein 1
1gxrA, 2ce8A, 2ce9A, 4om2A, 4om3A.
47.
Q9UMS4 PRP19_HUMAN Pre-mRNA-processing factor 19
4lg8A.
48.
P50851 LRBA_HUMAN Lipopolysaccharide-responsive and beige-like anchor protein
1t77A.
49.
Q8NFP9 NBEA_HUMAN Neurobeachin
1mi1A.
50.
Q8LNY6 Q8LNY6_WHEAT G protein beta subunit
3iz6a, 3j60g.
51.
P62881 GBB5_MOUSE Guanine nucleotide-binding protein subunit beta-5
2pbiB.
52.
Q8N157 AHI1_HUMAN Jouberin
4esrA.
53.
Q9V3J8 WDS_DROME Protein will die slowly
4cy3A, 4cy5A.
54.
Q8N5D0 WDTC1_HUMAN WD and tetratricopeptide repeats protein 1
3i7nB.
55.
P87314 HIR1_SCHPO Protein hir1
2z34C.
56.
P54198 HIRA_HUMAN Protein HIRA
2i32E.
57.
Q8IZQ1 WDFY3_HUMAN WD repeat and FYVE domain-containing protein 3
3wimB.
58.
P47025 MDV1_YEAST Mitochondrial division protein 1
2pqnB, 2xu6A, 3uuxB.
59.
Q11176 WDR1_CAEEL Actin-interacting protein 1
1nr0A, 1pevA.
60.
Q96WV5 COPA_SCHPO Putative coatomer subunit alpha
4j87A, 4j8bA, 4j8gA.
 
Q27954 COPA_BOVIN Coatomer subunit alpha
3mkrB.
61.
Q9Y263 PLAP_HUMAN Phospholipase A-2-activating protein
2k89A, 2k8aA, 2k8bB, 2k8cB, 3ebbA.
62.
O60907 TBL1X_HUMAN F-box-like/WD repeat-containing protein TBL1X
2xtcA, 2xtdA, 2xteA.
 
P63005 LIS1_MOUSE Platelet-activating factor acetylhydrolase IB subunit alpha
1uujA, 1vyhC.
63.
P38129 TAF5_YEAST Transcription initiation factor TFIID subunit 5
2j49A.
64.
P16649 TUP1_YEAST General transcriptional corepressor TUP1
1erjA, 3vp8A, 3vp9A.
65.
Q15542 TAF5_HUMAN Transcription initiation factor TFIID subunit 5
2nxpA.
66.
Q8WWQ0 PHIP_HUMAN PH-interacting protein
3mb3A.
67.
Q969H0 FBXW7_HUMAN F-box/WD repeat-containing protein 7
2ovpB, 2ovqB, 2ovrB.
68.
O43172 PRP4_HUMAN U4/U6 small nuclear ribonucleoprotein Prp4
1mzwB.
69.
P42527 MHCKA_DICDI Myosin heavy chain kinase A (E.C. 2.7.11.7)
3lkmA, 3llaA, 3lmhA, 3lmiA, 3pdtA.
70.
Q9BZK7 TBL1R_HUMAN F-box-like/WD repeat-containing protein TBL1XR1
4lg9A.
71.
P25382 NLE1_YEAST Ribosome assembly protein 4
3j65q.
72.
Q9Y297 FBW1A_HUMAN F-box/WD repeat-containing protein 1A
1p22A, 2p64A.
73.
P07834 CDC4_YEAST Cell division control protein 4
1nexB, 2p63A, 3mksB, 3v7dB.
74.
Q9NSI6 BRWD1_HUMAN Bromodomain and WD repeat-containing protein 1
3q2eA.
75.
O88879 APAF_MOUSE Apoptotic protease-activating factor 1
3sfzA, 3shfA.
 
O14727 APAF_HUMAN Apoptotic protease-activating factor 1
1c15A, 1cwwA, 1cy5A, 1z6tA, 2p1hA, 2ygsA, 3iytA, 3izaA, 3j2tA, 3ygsC.
76.
B2J0I0 B2J0I0_NOSP7 WD-40 repeat protein
2ymuA.
77.
Q15751 HERC1_HUMAN Probable E3 ubiquitin-protein ligase HERC1 (E.C. 6.3.2.-)
4o2wA.

List of Pfam domains

  Pfam code Pfam id Description
PF00400 WD40 WD domain, G-beta repeat
PF00018 SH3_1 SH3 domain
PF00160 Pro_isomerase Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
PF00415 RCC1 Regulator of chromosome condensation (RCC1) repeat
PF00439 Bromodomain Bromodomain
PF00505 HMG_box HMG (high mobility group) box
PF00619 CARD Caspase recruitment domain
PF00622 SPRY SPRY domain
PF00632 HECT HECT-domain (ubiquitin-transferase)
PF00646 F-box F-box domain
PF00931 NB-ARC NB-ARC domain
PF01363 FYVE FYVE zinc finger
PF02138 Beach Beige/BEACH domain
PF02816 Alpha_kinase Alpha-kinase family
PF03451 HELP HELP motif
PF03920 TLE_N Groucho/TLE N-terminal Q-rich domain
PF04053 Coatomer_WDAD Coatomer WD associated region
PF04192 Utp21 Utp21 specific WD40 associated putative domain
PF04494 TFIID_90kDa WD40 associated region in TFIID subunit
PF04564 U-box U-box domain
PF05262 Borrelia_P83 Borrelia P83/100 protein
PF06469 DUF1088 Domain of Unknown Function (DUF1088)
PF06957 COPI_C Coatomer (COPI) alpha subunit C-terminus
PF07304 SRA1 Steroid receptor RNA activator (SRA1)
PF07569 Hira TUP1-like enhancer of split
PF07719 TPR_2 Tetratricopeptide repeat
PF08154 NLE NLE (NUC135) domain
PF08232 Striatin Striatin family
PF08324 PUL PUL domain
PF08366 LLGL LLGL2
PF08513 LisH LisH
PF08581 Tup_N Tup N-terminal
PF08596 Lgl_C Lethal giant larvae(Lgl) like, C-terminal
PF08606 Prp19 Prp19/Pso4-like
PF08614 ATG16 Autophagy protein 16 (ATG16)
PF08662 eIF2A Eukaryotic translation initiation factor eIF2A
PF08799 PRP4 pre-mRNA processing factor 4 (PRP4) like
PF08953 DUF1899 Domain of unknown function (DUF1899)
PF08954 DUF1900 Domain of unknown function (DUF1900)
PF09070 PFU PFU (PLAA family ubiquitin binding)
PF09453 HIRA_B HIRA B motif
PF11540 Dynein_IC2 Cytoplasmic dynein 1 intermediate chain 2
PF11542 Mdv1 Mitochondrial division protein 1
PF11549 Sec31 Protein transport protein SEC31
PF11615 DUF3249 Protein of unknown function (DUF3249)
PF12125 Beta-TrCP_D D domain of beta-TrCP
PF12265 CAF1C_H4-bd Histone-binding protein RBBP4 or subunit C of CAF1 complex
PF12341 DUF3639 Protein of unknown function (DUF3639)
PF12937 F-box-like F-box-like
PF13385 Laminin_G_3 Concanavalin A-like lectin/glucanases superfamily
PF13414 TPR_11 TPR repeat
PF14516 AAA_35 AAA-like domain
PF14844 PH_BEACH PH domain associated with Beige/BEACH
PB000024
PB000048
PB000071
PB000164
PB001048
PB001633
PB002526
PB002765
PB003044
PB003640
PB004388
PB005259
PB005523
PB006516
PB006630
PB006684
PB007379
PB007799
PB008023
PB008184
PB009275
PB009849
PB012750
PB013457
PB014124
PB015233
PB015784
PB015799
PB016974
PB017313
PB017538
PB017771
PB017910
PB018560
PB018921
PB018973
PB019724
PB020425
PB020673
PB021008
PB021666
PB022078
PB022190
PB023174
PB023308
PB023697
PB024992
PB026038
PB026289
PB027858
PB027981
PB028416
PB030705
PB034272
PB034285
PB034937
PB034995
PB036138
PB038882
PB044541
PB046962
PB056042
PB060496
PB060538
PB063758
PB066553
PB066738
PB069182
PB071498
PB074206
PB079993
PB079995
PB081415
PB098353
PB331331
PB395425

 

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