spacer
spacer

Pfam domain PF00373

Pfam domain PF00373

Pfam domain:   
  PF00373 - FERM central domain  

Below is the list of protein structures in the PDB containing Pfam domain PF00373.

+/- Key to table

Structures in the PDB containing this domain: 184

  Pfam domain
architecture
UniProt
accession
UniProt id Protein name PDB structures
1.
O00522 KRIT1_HUMAN Krev interaction trapped protein 1
3u7dA, 4dx8H, 4dxaB, 4hdoA, 4hdqA, 4jifB.
2.
Q86UX7 URP2_HUMAN Fermitin family homolog 3
2ys3A.
3.
P59113 FERM1_MOUSE Fermitin family homolog 1
2kmcA.
4.
Q05397 FAK1_HUMAN Focal adhesion kinase 1 (E.C. 2.7.10.2)
1k04A, 1k05A, 1mp8A, 1ow6A, 1ow7A, 1ow8A, 2etmA, 2ijmA, 2ra7A, 3b71A, 3bz3A, 3pxkA, 3s9oA, 4ebvA, 4ebwA, 4gu6A, 4gu9A, 4i4eA, 4i4fA, 4k8aA, 4k9yA, 4kabA, 4kaoA, 4ny0D, 4q9sA.
 
Q00944 FAK1_CHICK Focal adhesion kinase 1 (E.C. 2.7.10.2)
1ktmA, 1pv3A, 1qvxA, 2aehA, 2al6A, 2j0jA, 2j0kA, 2j0lA, 2j0mA, 2jkkA, 2jkmA, 2jkoA, 2jkqA, 2l6fA, 2l6gA, 2l6hA, 3zdtA, 4brxA, 4c7tA, 4cyeA.
 
P34152 FAK1_MOUSE Focal adhesion kinase 1 (E.C. 2.7.10.2)
1k40A, 1kkyB, 1kl0A.
5.
Q8WY64 MYLIP_HUMAN E3 ubiquitin-protein ligase MYLIP (E.C. 6.3.2.-)
2yhnA, 2yhoA.
6.
Q96AC1 FERM2_HUMAN Fermitin family homolog 2
2lgxA, 2lkoA, 2msuA, 4f7hA.
7.
Q5SYB0 FRPD1_HUMAN FERM and PDZ domain-containing protein 1
2edvA, 4g2vB.
8.
Q14289 FAK2_HUMAN Protein-tyrosine kinase 2-beta (E.C. 2.7.10.2)
2fo6X, 2lk4A, 3cc6A, 3et7A, 3fzoA, 3fzpA, 3fzrA, 3fzsA, 3fztA, 3gm1A, 3gm2A, 3gm3A, 3h3cA, 3u3cA, 3u3fA, 4ekuA, 4h1jA, 4h1mA, 4r32A.
9.
Q15678 PTN14_HUMAN Tyrosine-protein phosphatase non-receptor type 14 (E.C. 3.1.3.48)
2bzlA.
10.
P26043 RADI_MOUSE Radixin
1gc6A, 1gc7A, 1j19A, 2d10A, 2d11A, 2d2qA, 2emsA, 2emtA, 2yvcA, 2zpyA.
 
P15311 EZRI_HUMAN Ezrin
1ni2A.
 
P26038 MOES_HUMAN Moesin
1e5wA, 1ef1A, 1sghA.
 
A0T1L9 A0T1L9_SPOFR Moesin {ECO:0000313|EMBL:ABK60307.1}
2i1jA, 2i1kA.
 
P35240 MERL_HUMAN Merlin
1h4rA, 3u8zA.
 
P46662 MERL_MOUSE Merlin
1isnA, 3wa0A, 4p7iA.
11.
Q9FHN8 KCBP_ARATH Kinesin-like calmodulin-binding protein
3h4sA, 4frzA.
12.
Q41460 Q41460_SOLTU Kinesin heavy chain-like protein {ECO:0000313|EMBL:AAB37756.1}
1sdmA, 3cnzA, 3cobA.
13.
P26045 PTN3_HUMAN Tyrosine-protein phosphatase non-receptor type 3 (E.C. 3.1.3.48)
2b49A.
14.
P11171 41_HUMAN Protein 4.1
1gg3A, 2rq1A, 3qijA.
15.
Q9VSL8 Q9VSL8_DROME Rhea, isoform B {ECO:0000313|EMBL:AFH04345.1}
3fyqA.
16.
P29074 PTN4_HUMAN Tyrosine-protein phosphatase non-receptor type 4 (E.C. 3.1.3.48)
2cs5A, 2i75A, 2vphA, 3nfkA, 3nflA.
17.
P54939 TLN1_CHICK Talin-1
1mixA, 1mizB, 1mk7B, 1mk9B, 1rkcB, 1u6hB, 1xwjB, 1zvzB, 1zw2B, 2h7dA, 2h7eA, 2hrjA, 2k00A.
18.
Q91VS8 FARP2_MOUSE FERM, RhoGEF and pleckstrin domain-containing protein 2
4gyvA, 4gzuA.
19.
Q9Y2J2 E41L3_HUMAN Band 4.1-like protein 3
2he7A, 3binA.
20.
Q9Y490 TLN1_HUMAN Talin-1
1syqB, 4dj9B.
 
Q71LX4 TLN2_MOUSE Talin-2
3g9wA.
 
P26039 TLN1_MOUSE Talin-1
1sj7A, 1sj8A, 1t01B, 1u89A, 1xwxA, 1y19B, 1zw3B, 2b0hA, 2g35A, 2jswA, 2kbbA, 2kc1A, 2kc2A, 2kgxA, 2kmaA, 2kvpA, 2l10A, 2l7aA, 2l7nA, 2lqgA, 2qdqA, 2x0cA, 3dyjA, 3ivfA, 3s90C, 4f7gA.
21.
Q9Y4F1 FARP1_HUMAN FERM, RhoGEF and pleckstrin domain-containing protein 1
4h6yA.
22.
P97479 MYO7A_MOUSE Unconventional myosin-VIIa
3pvlA.
23.
Q64512 PTN13_MOUSE Tyrosine-protein phosphatase non-receptor type 13 (E.C. 3.1.3.48)
1gm1A, 1oziA, 1vj6A.
 
Q12923 PTN13_HUMAN Tyrosine-protein phosphatase non-receptor type 13 (E.C. 3.1.3.48)
1d5gA, 1q7xA, 1wchA, 2m0zA, 2m10A, 3lnxA, 3lnyA, 3pdzA.
24.
Q9HD67 MYO10_HUMAN Unconventional myosin-X
2lw9A, 3au4A, 3au5A, 3pzdA.
 
D3ZJP6 MYO10_RAT Unconventional myosin-X
3tfmA.

List of Pfam domains

  Pfam code Pfam id Description
PF00373 FERM_M FERM central domain
PF00023 Ank Ankyrin repeat
PF00063 Myosin_head Myosin head (motor domain)
PF00102 Y_phosphatase Protein-tyrosine phosphatase
PF00169 PH PH domain
PF00225 Kinesin Kinesin motor domain
PF00595 PDZ PDZ domain (Also known as DHR or GLGF)
PF00612 IQ IQ calmodulin-binding motif
PF00621 RhoGEF RhoGEF domain
PF00769 ERM Ezrin/radixin/moesin family
PF00784 MyTH4 MyTH4 domain
PF01608 I_LWEQ I/LWEQ domain
PF02174 IRS PTB domain (IRS-1 type)
PF03623 Focal_AT Focal adhesion targeting region
PF04382 SAB SAB domain
PF05902 4_1_CTD 4.1 protein C-terminal domain (CTD)
PF07714 Pkinase_Tyr Protein tyrosine kinase
PF08736 FA FERM adjacent (FA)
PF08913 VBS Vinculin Binding Site
PF09141 Talin_middle Talin, middle domain
PF09379 FERM_N FERM N-terminal domain
PF09380 FERM_C FERM C-terminal PH-like domain
PF13920 zf-C3HC4_3 Zinc finger, C3HC4 type (RING finger)
PB001600
PB002102
PB002357
PB003813
PB004507
PB006385
PB006471
PB007251
PB008368
PB009399
PB011875
PB016217
PB020401
PB022492
PB022907
PB028526
PB028862
PB035862
PB213640
PB315767

 

spacer
spacer