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Pfam domain PF00168

Pfam domain PF00168

Pfam domain:   
  PF00168 - C2 domain  

Below is the list of protein structures in the PDB containing Pfam domain PF00168.

+/- Key to table

Structures in the PDB containing this domain: 226

  Pfam domain
architecture
UniProt
accession
UniProt id Protein name PDB structures
1.
E2FYL5 E2FYL5_PSEMX C2 domain protein
3w56A, 3w57A.
 
Q9C8S6 Y1322_ARATH C2 domain-containing protein At1g63220
1wfjA.
2.
Q7L8C5 SYT13_HUMAN Synaptotagmin-13
1wfmA.
 
Q9H2B2 SYT4_HUMAN Synaptotagmin-4
1ugkA.
 
Q14183 DOC2A_HUMAN Double C2-like domain-containing protein alpha
4mjjA.
 
P50232 SYT4_RAT Synaptotagmin-4
1w15A, 1w16A.
3.
P47712 PA24A_HUMAN Cytosolic phospholipase A2 (E.C. 3.1.1.4, 3.1.1.5)
1bciA, 1cjyA, 1rlwA.
4.
Q9H0E2 TOLIP_HUMAN Toll-interacting protein
1wglA.
5.
Q7L804 RFIP2_HUMAN Rab11 family-interacting protein 2
2gzdC, 2gzhB, 2k6sA, 3tsoC, 4c4pB.
6.
P46097 SYT2_MOUSE Synaptotagmin-2
2np0B, 4kbbC.
 
P21707 SYT1_RAT Synaptotagmin-1
1bynA, 1k5wA, 1rsyA, 1tjmA, 1tjxA, 1uovA, 1uowA, 2yoaA.
 
P29101 SYT2_RAT Synaptotagmin-2
2nm1B, 4isrD.
 
P21579 SYT1_HUMAN Synaptotagmin-1
2k45A, 2k4aA, 2k8mA, 2ki6A, 2lhaA, 2r83A, 3f00A, 3f01A, 3f04A, 3f05A, 4isqD.
7.
Q68CZ1 FTM_HUMAN Protein fantom
2yrbA.
8.
O43581 SYT7_HUMAN Synaptotagmin-7
2d8kA.
 
Q9R0N7 SYT7_MOUSE Synaptotagmin-7
3n5aA.
9.
P70610 DOC2B_RAT Double C2-like domain-containing protein beta
4lcvA, 4ldcA.
10.
P10820 PERF_MOUSE Perforin-1
3nsjA.
11.
P40748 SYT3_RAT Synaptotagmin-3
1dqvA, 3hn8A.
12.
P49796 RGS3_HUMAN Regulator of G-protein signaling 3
2f5yA, 2oj4A, 3fbkA.
13.
Q9QUH6 SYGP1_RAT Ras/Rap GTPase-activating protein SynGAP
3bxjA.
14.
P47709 RP3A_RAT Rabphilin-3A
1zbdB, 2chdA, 2cm5A, 2cm6A, 3rpbA, 4lt7A, 4np9A, 4ns0A.
 
P47708 RP3A_MOUSE Rabphilin-3A
2k3hA.
 
Q96C24 SYTL4_HUMAN Synaptotagmin-like protein 4
2cszA, 3fdwA.
 
Q9HCH5 SYTL2_HUMAN Synaptotagmin-like protein 2
3bc1B.
15.
Q9BSW7 SYT17_HUMAN Synaptotagmin-17
2enpA.
16.
Q6DN12 MCTP2_HUMAN Multiple C2 and transmembrane domain-containing protein 2
2ep6A.
17.
Q9HCE7 SMUF1_HUMAN E3 ubiquitin-protein ligase SMURF1 (E.C. 6.3.2.-)
2lazA, 2lb0A, 2lb1A, 2ltxA, 3pycA.
18.
Q59F77 Q59F77_HUMAN Phosphoinositide phospholipase C (E.C. 3.1.4.11)
2zkmX.
19.
A0FGR8 ESYT2_HUMAN Extended synaptotagmin-2
2dmgA, 4npjA, 4npkA, 4p42A.
20.
Q76N89 HECW1_HUMAN E3 ubiquitin-protein ligase HECW1 (E.C. 6.3.2.-)
3l4hA.
21.
Q86UR5 RIMS1_HUMAN Regulating synaptic membrane exocytosis protein 1
2cssA.
 
Q9JIR4 RIMS1_RAT Regulating synaptic membrane exocytosis protein 1
1zubA, 2q3xA.
22.
P05129 KPCG_HUMAN Protein kinase C gamma type (E.C. 2.7.11.13)
2e73A, 2uzpA.
 
P05696 KPCA_RAT Protein kinase C alpha type (E.C. 2.7.11.13)
1dsyA, 3gpeA, 3rdjA, 3rdlA, 3twyA, 4l1lA.
 
P05771 KPCB_HUMAN Protein kinase C beta type (E.C. 2.7.11.13)
2i0eA.
 
P68403 KPCB_RAT Protein kinase C beta type (E.C. 2.7.11.13)
1a25A, 3pfqA.
 
P17252 KPCA_HUMAN Protein kinase C alpha type (E.C. 2.7.11.13)
2eliA, 3iw4A, 4dnlA.
 
P63319 KPCG_RAT Protein kinase C gamma type (E.C. 2.7.11.13)
1tbnA, 1tboA.
23.
Q02156 KPCE_HUMAN Protein kinase C epsilon type (E.C. 2.7.11.13)
2wh0Q.
 
P09216 KPCE_RAT Protein kinase C epsilon type (E.C. 2.7.11.13)
1gmiA.
 
P24723 KPCL_HUMAN Protein kinase C eta type (E.C. 2.7.11.13)
2fk9A, 3txoA.
24.
Q62940 NEDD4_RAT E3 ubiquitin-protein ligase NEDD4 (E.C. 6.3.2.-)
1i5hW.
 
P39940 RSP5_YEAST E3 ubiquitin-protein ligase RSP5 (E.C. 6.3.2.-)
3olmA, 4lcdA.
 
P46935 NEDD4_MOUSE E3 ubiquitin-protein ligase NEDD4 (E.C. 6.3.2.-)
3m7fB.
 
Q9HAU4 SMUF2_HUMAN E3 ubiquitin-protein ligase SMURF2 (E.C. 6.3.2.-)
1zvdA, 2djyA, 2jqzA, 2kxqA, 2ltzA.
25.
P11274 BCR_HUMAN Breakpoint cluster region protein (E.C. 2.7.11.1)
1k1fA.
26.
F2YQ19 F2YQ19_SEPOF Phosphoinositide phospholipase C (E.C. 3.1.4.11)
3qr0A.
 
Q9NBA8 Q9NBA8_DORPE Phosphoinositide phospholipase C (E.C. 3.1.4.11)
3qr1A.
27.
Q91086 Q91086_MELGA Phosphoinositide phospholipase C (E.C. 3.1.4.11)
1jadA.
 
Q00722 PLCB2_HUMAN 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 (E.C. 3.1.4.11)
2fjuB, 2zkmX.
28.
Q9VVI3 NEDD4_DROME E3 ubiquitin-protein ligase Nedd-4 (E.C. 6.3.2.-)
2ez5W.
29.
Q62768 UN13A_RAT Protein unc-13 homolog A
1y8fA, 2cjsA, 2cjtA, 2kduB, 3kwtA, 3kwuA, 3swhA.
30.
Q9Y0H4 SUDX_DROME E3 ubiquitin-protein ligase Su(dx) (E.C. 6.3.2.-)
1tk7A, 2jmfA.
 
Q8CFI0 NED4L_MOUSE E3 ubiquitin-protein ligase NEDD4-like (E.C. 6.3.2.-)
1wr3A, 1wr4A, 1wr7A.
 
Q8C863 ITCH_MOUSE E3 ubiquitin-protein ligase Itchy (E.C. 6.3.2.-)
1yiuA, 2jo9A, 2jocA.
 
Q96J02 ITCH_HUMAN E3 ubiquitin-protein ligase Itchy homolog (E.C. 6.3.2.-)
2dmvA, 2kykA, 2nq3A, 2p4rT, 2ysfA, 3tugA.
 
Q96PU5 NED4L_HUMAN E3 ubiquitin-protein ligase NEDD4-like (E.C. 6.3.2.-)
2lajA, 2lb2A, 2ltyA, 2nsqA, 2oniA, 3jvzC, 3jw0C.
31.
P10688 PLCD1_RAT 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 (E.C. 3.1.4.11)
1djgA, 1djhA, 1djiA, 1djwA, 1djxA, 1djyA, 1djzA, 1isdA, 1maiA, 1qasA, 1qatA, 2isdA.
32.
Q01970 PLCB3_HUMAN 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 (E.C. 3.1.4.11)
3ohmB, 4gnkB.
33.
Q9P2P5 HECW2_HUMAN E3 ubiquitin-protein ligase HECW2 (E.C. 6.3.2.-)
2lfeA.
34.
Q9JIS1 RIMS2_RAT Regulating synaptic membrane exocytosis protein 2
2a20A, 2bwqA, 2cjsC.
35.
Q61194 P3C2A_MOUSE Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (E.C. 2.7.1.154)
2b3rA.
 
O00443 P3C2A_HUMAN Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (E.C. 2.7.1.154)
2ar5A, 2iwlX, 2reaA, 2redA.
36.
P20936 RASA1_HUMAN Ras GTPase-activating protein 1
1werA, 1wq1G, 2gqiA, 2j05A, 2j06A, 2m51A, 4fssA.
37.
Q9H0M0 WWP1_HUMAN NEDD4-like E3 ubiquitin-protein ligase WWP1 (E.C. 6.3.2.-)
1nd7A, 2op7A.
38.
Q9UQ26 RIMS2_HUMAN Regulating synaptic membrane exocytosis protein 2
1v27A, 1wfgA.
39.
Q9Y6V0 PCLO_HUMAN Protein piccolo
1ujdA.
40.
Q8CIH5 PLCG2_MOUSE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (E.C. 3.1.4.11)
2dx0A, 2eqiA.
 
P24135 PLCG2_RAT 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (E.C. 3.1.4.11)
2eobA.
 
P16885 PLCG2_HUMAN 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (E.C. 3.1.4.11)
2k2jA, 2w2wA, 2w2xC.
41.
P19174 PLCG1_HUMAN 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (E.C. 3.1.4.11)
1hsqA, 2hspA, 4ey0A, 4fbnA.
 
P08487 PLCG1_BOVIN 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (E.C. 3.1.4.11)
2fciA, 2pldA, 2pleA.
42.
Q9JKS6 PCLO_RAT Protein piccolo
1rh8A.
43.
P10686 PLCG1_RAT 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (E.C. 3.1.4.11)
1y0mA, 1ywoA, 1ywpA, 2fjlA, 3gqiB, 4k44A, 4k45A.
44.
Q9P212 PLCE1_HUMAN 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 (E.C. 3.1.4.11)
2byeA, 2byfA, 2c5lC.
45.
Q9Z0R4 ITSN1_MOUSE Intersectin-1
3hs8P, 3jv3A.
46.
Q15811 ITSN1_HUMAN Intersectin-1
1ki1B, 2kgrA, 2khnA, 3fiaA, 3qbvB, 4iimA.
47.
Q9ERC5 OTOF_RAT Otoferlin
3l9bA.
48.
Q9NZM3 ITSN2_HUMAN Intersectin-2
1j3tA, 1udlA, 1ue9A, 1uffA, 1uhfA, 3gf9A, 3jzyA, 4iioA.
49.
Q9NZM1 MYOF_HUMAN Myoferlin
2dmhA, 2k2oA.
50.
O75923 DYSF_HUMAN Dysferlin
4cahB, 4caiA, 4ihbA, 4iqhA.

List of Pfam domains

  Pfam code Pfam id Description
PF00168 C2 C2 domain
PF00017 SH2 SH2 domain
PF00018 SH3_1 SH3 domain
PF00069 Pkinase Protein kinase domain
PF00130 C1_1 Phorbol esters/diacylglycerol binding domain (C1 domain)
PF00169 PH PH domain
PF00387 PI-PLC-Y Phosphatidylinositol-specific phospholipase C, Y domain
PF00388 PI-PLC-X Phosphatidylinositol-specific phospholipase C, X domain
PF00397 WW WW domain
PF00433 Pkinase_C Protein kinase C terminal domain
PF00454 PI3_PI4_kinase Phosphatidylinositol 3- and 4-kinase
PF00595 PDZ PDZ domain (Also known as DHR or GLGF)
PF00613 PI3Ka Phosphoinositide 3-kinase family, accessory domain (PIK domain)
PF00615 RGS Regulator of G protein signaling domain
PF00616 RasGAP GTPase-activator protein for Ras-like GTPase
PF00617 RasGEF RasGEF domain
PF00620 RhoGAP RhoGAP domain
PF00621 RhoGEF RhoGEF domain
PF00632 HECT HECT-domain (ubiquitin-transferase)
PF00787 PX PX domain
PF00788 RA Ras association (RalGDS/AF-6) domain
PF00792 PI3K_C2 Phosphoinositide 3-kinase C2
PF00794 PI3K_rbd PI3-kinase family, ras-binding domain
PF01735 PLA2_B Lysophospholipase catalytic domain
PF01823 MACPF MAC/Perforin domain
PF02318 FYVE_2 FYVE-type zinc finger
PF02845 CUE CUE domain
PF05715 zf-piccolo Piccolo Zn-finger
PF06292 DUF1041 Domain of Unknown Function (DUF1041)
PF06398 Pex24p Integral peroxisomal membrane peroxin
PF06631 DUF1154 Protein of unknown function (DUF1154)
PF07653 SH3_2 Variant SH3 domain
PF08150 FerB FerB (NUC096) domain
PF08151 FerI FerI (NUC094) domain
PF08165 FerA FerA (NUC095) domain
PF08372 PRT_C Plant phosphoribosyltransferase C-terminal
PF08703 PLC-beta_C PLC-beta C terminal
PF09036 Bcr-Abl_Oligo Bcr-Abl oncoprotein oligomerisation domain
PF09279 EF-hand_like Phosphoinositide-specific phospholipase C, efhand-like
PF09457 RBD-FIP FIP domain
PF10540 Membr_traf_MHD Munc13 (mammalian uncoordinated) homology domain
PF11618 DUF3250 Protein of unknown function (DUF3250)
PF12004 DUF3498 Domain of unknown function (DUF3498)
PF12763 EF-hand_4 Cytoskeletal-regulatory complex EF hand
PF14604 SH3_9 Variant SH3 domain
PF14788 EF-hand_10 EF hand
PB000118
PB000462
PB002211
PB003372
PB003636
PB003731
PB004130
PB006263
PB006991
PB008101
PB009076
PB009276
PB009624
PB009683
PB011590
PB011861
PB013774
PB013936
PB015219
PB016403
PB017545
PB018277
PB020397
PB022026
PB022904
PB024454
PB027064
PB032198
PB032498
PB036002
PB038282
PB038646
PB045830
PB061730
PB083621
PB275100
PB339434

 

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