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Pfam domain PF00104

Pfam domain PF00104

Pfam domain:   
  PF00104 - Ligand-binding domain of nuclear hormone receptor  

Below is the list of protein structures in the PDB containing Pfam domain PF00104.

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Structures in the PDB containing this domain: 834

  Pfam domain
architecture
UniProt
accession
UniProt id Protein name PDB structures
1.
H0USY8 H0USY8_9BILA aceDAF-12
3up0A, 3up3A.
 
Q62227 NR0B2_MOUSE Nuclear receptor subfamily 0 group B member 2
4nufA.
 
P97947 NR0B2_RAT Nuclear receptor subfamily 0 group B member 2
1yp0B, 1zgyB, 1zh7C.
 
Q15466 NR0B2_HUMAN Nuclear receptor subfamily 0 group B member 2
1yucC, 4dorC.
 
Q7SIF6 Q7SIF6_HELVI Gene regulation protein
1g2nA, 1r1kA, 1r20A, 2r40A, 3ixpA, 4ummF.
2.
A1JUG3 A1JUG3_TRICA Ecdysone receptor (Isoform A)
2nxxE.
 
E0VVT4 E0VVT4_PEDHC Ecdysone receptor, putative
4ozrE, 4oztE.
 
P04625 THA_CHICK Thyroid hormone receptor alpha
3uvvA.
 
O18473 ECR_HELVI Ecdysone receptor
1r1kD, 1r20D, 2r40D, 4ummE.
 
P51449 RORG_HUMAN Nuclear receptor ROR-gamma
3b0wA, 3kytA, 3l0jA, 4nb6A, 4nieA.
 
Q07869 PPARA_HUMAN Peroxisome proliferator-activated receptor alpha
1i7gA, 1k7lA, 1kkqA, 2npaA, 2p54A, 2rewA, 2znnA, 3et1A, 3feiA, 3g8iA, 3kdtA, 3kduA, 3sp6A, 3vi8A, 4bcrA.
 
A2A113 A2A113_CRAGI Estrogen receptor
3ltxA.
 
O00482 NR5A2_HUMAN Nuclear receptor subfamily 5 group A member 2
1yokA, 1yucA, 1zduA, 2a66A, 3plzA, 3tx7B, 4dorA, 4dosA, 4is8A.
 
P10826 RARB_HUMAN Retinoic acid receptor beta
1hraA, 1xapA, 4dm6A, 4dm8A, 4jygA, 4jyhA, 4jyiA.
 
Q14994 NR1I3_HUMAN Nuclear receptor subfamily 1 group I member 3
1xv9B, 1xvpB.
 
F1D8P7 F1D8P7_HUMAN Liver X nuclear receptor beta
4nqaB.
 
P62508 ERR3_HUMAN Estrogen-related receptor gamma
1kv6A, 1tfcA, 1vjbA, 2e2rA, 2ewpA, 2gp7A, 2gpoA, 2gppA, 2gpuA, 2gpvA, 2p7aA, 2p7gA, 2p7zA, 2zasA, 2zbsA, 2zkcA.
 
P11474 ERR1_HUMAN Steroid hormone receptor ERR1
1xb7A, 2pjlA, 3d24A, 3k6pA.
 
P13053 VDR_RAT Vitamin D3 receptor
1rjkA, 1rk3A, 1rkgA, 1rkhA, 2o4jA, 2o4rA, 2zfxA, 2zl9A, 2zlaA, 2zlcA, 2zmhA, 2zmiA, 2zmjA, 2zxmA, 2zxnA, 3a2hA, 3afrA, 3aunA, 3vjsA, 3vjtA, 3vrtA, 3vruA, 3vrvA, 3vrwA, 3vt3A, 3vt4A, 3vt5A, 3vt6A, 3vt7A, 3vt8A, 3vt9A, 3vtbA, 3vtcA, 3vtdA, 3w0gA, 3w0hA, 3w0iA, 3w0jA, 3w5pA, 3w5qA, 3w5rA, 3w5tA, 3wt5A, 3wt6A, 3wt7A.
 
P08235 MCR_HUMAN Mineralocorticoid receptor
1y9rA, 1ya3A, 2a3iA, 2aa2A, 2aa5A, 2aa6A, 2aa7A, 2aaxA, 2ab2A, 2abiA, 2oaxA, 3vhuA, 3vhvA, 3wffA, 3wfgA.
 
O75469 NR1I2_HUMAN Nuclear receptor subfamily 1 group I member 2
1ilgA, 1ilhA, 1m13A, 1nrlA, 1skxA, 2o9iA, 2qnvA, 3ctcA, 3r8dA, 4j5wA.
 
O95718 ERR2_HUMAN Steroid hormone receptor ERR2
1lo1A.
 
B9UCQ4 B9UCQ4_HELAM Ecdysone receptor
3ixpD.
 
Q8IVZ9 Q8IVZ9_HUMAN NR2E3 protein
4logA.
 
P20153 USP_DROME Protein ultraspiracle
1hg4A, 1r0oA, 2hanA.
 
P20393 NR1D1_HUMAN Nuclear receptor subfamily 1 group D member 1
1a6yA, 1ef6A, 1ga5A, 1hlzA, 3n00A.
 
P55055 NR1H2_HUMAN Oxysterols receptor LXR-beta
1p8dA, 1pq6A, 1pq9A, 1pqcA, 1upvA, 1upwA, 3kfcA, 3l0eA, 4dk7A, 4dk8A.
 
P62509 ERR3_MOUSE Estrogen-related receptor gamma
1s9pA, 1s9qA.
 
P22736 NR4A1_HUMAN Nuclear receptor subfamily 4 group A member 1
2gbdA, 2qw4A, 3v3eB, 3v3qA, 4jgvA.
 
P22829 NR4A1_RAT Nuclear receptor subfamily 4 group A member 1
1citA, 1yjeA.
 
A1JUG2 A1JUG2_TRICA Ultraspiracle nuclear receptor
2nxxA.
 
P24468 COT2_HUMAN COUP transcription factor 2
3cjwA.
 
P28702 RXRB_HUMAN Retinoic acid receptor RXR-beta
1h9uA, 1uhlA.
 
P33242 STF1_MOUSE Steroidogenic factor 1
1ymtA, 1yp0A, 2ff0A, 3f7dA.
 
E0VFQ5 E0VFQ5_PEDHC Retinoid X receptor, putative
4ozrU, 4oztU.
 
P34021 ECR_DROME Ecdysone receptor
1r0nB, 1r0oB, 2hanB.
 
P35398 RORA_HUMAN Nuclear receptor ROR-alpha
1n83A, 1s0xA.
 
P11473 VDR_HUMAN Vitamin D3 receptor
1db1A, 1ie8A, 1ie9A, 1kb2A, 1kb4A, 1kb6A, 1s0zA, 1s19A, 1txiA, 1ynwA, 2hamA, 2harA, 2hasA, 2hb7A, 2hb8A, 3a2iA, 3a2jA, 3a3zX, 3a40X, 3a78A, 3auqA, 3aurA, 3ax8A, 3az1A, 3az2A, 3az3A, 3b0tA, 3cs4A, 3cs6A, 3kpzA, 3m7rA, 3ogtA, 3p8xA, 3tkcA, 3vhwA, 3w0aA, 3w0cA, 3w0yA, 4g2iA, 4iteA, 4itfA.
 
Q60674 NR1D2_MOUSE Nuclear receptor subfamily 1 group D member 2
1efjA.
 
P43354 NR4A2_HUMAN Nuclear receptor subfamily 4 group A member 2
1ovlA.
 
O35627 NR1I3_MOUSE Nuclear receptor subfamily 1 group I member 3
1xlsE, 1xnxA.
 
P45448 NR5A2_MOUSE Nuclear receptor subfamily 5 group A member 2
1pk5A, 1zh7A, 3f5cA.
 
P10276 RARA_HUMAN Retinoic acid receptor alpha
1dkfB, 1dszA, 3a9eB, 3kmrA, 3kmzB, 4dqmA.
 
Q13285 STF1_HUMAN Steroidogenic factor 1
1yowA, 1zdtA, 4qjrA, 4qk4A.
 
Q9PTN2 VDRA_DANRE Vitamin D3 receptor A
2hbhA, 2hc4A, 2hcdA, 3dr1A, 3o1dA, 3o1eA, 4fhhA, 4fhiA, 4g1dA, 4g1yA, 4g1zA, 4g20A, 4g21A, 4g2hA, 4ia1A, 4ia2A, 4ia3A, 4ia7A, 4q0aC.
 
Q8MX78 Q8MX78_BRAFL Nuclear hormone receptor RXR
3eybA.
 
Q8T5C6 RXR_BIOGL Retinoic acid receptor RXR
1xiuA.
 
Q14995 NR1D2_HUMAN Nuclear receptor subfamily 1 group D member 2
2v0vA, 2v7cA, 3cqvA, 4n73A.
 
P22605 RARB_MOUSE Retinoic acid receptor beta
1xdkB.
 
P13631 RARG_HUMAN Retinoic acid receptor gamma
1exaA, 1exxA, 1fcxA, 1fcyA, 1fczA, 1fd0A, 2lbdA, 3lbdA, 4lbdA.
 
Q03181 PPARD_HUMAN Peroxisome proliferator-activated receptor delta
1gwxA, 1y0sA, 2awhA, 2b50A, 2bawA, 2envA, 2gwxA, 2j14A, 2q5gA, 2xyjA, 2xywA, 2xyxA, 2znpA, 2znqA, 3d5fA, 3dy6A, 3et2A, 3gwxA, 3gz9A, 3oz0A, 3peqA, 3sp9A, 3tkmA.
 
Q9UAF1 Q9UAF1_POLMI Retinoid X receptor
2q60A.
3.
Q62735 NR1H4_RAT Bile acid receptor
1osvA, 1ot7A.
 
Q96RI1 NR1H4_HUMAN Bile acid receptor
1oshA, 1oskA, 3bejA, 3dctA, 3dcuA, 3fliA, 3fxvA, 3gd2A, 3hc5A, 3hc6A, 3l1bA, 3okhA, 3okiA, 3olfA, 3omkA, 3ommA, 3oofA, 3ookA, 3p88A, 3p89A, 3rutA, 3ruuA, 3rvfA, 4ii6A.
4.
P49116 NR2C2_HUMAN Nuclear receptor subfamily 2 group C member 2
3p0uA.
5.
Q9Z0Y9 NR1H3_MOUSE Oxysterols receptor LXR-alpha
2aclB, 3falB, 3fc6B.
 
Q13133 NR1H3_HUMAN Oxysterols receptor LXR-alpha
1uhlB, 3ipqA, 3ipsA, 3ipuA.
6.
P18113 THB_RAT Thyroid hormone receptor beta
3m9eA.
 
P10828 THB_HUMAN Thyroid hormone receptor beta
1bsxA, 1n46A, 1naxA, 1nq0A, 1nq1A, 1nq2A, 1nuoA, 1q4xA, 1r6gA, 1xzxX, 1y0xX, 2h6wX, 2j4aA, 2nllB, 2pinA, 3d57A, 3gwsX, 3imyA, 3jzcA.
7.
P33244 FTZF1_DROME Nuclear hormone receptor FTZ-F1
2iz2A, 2xhsA.
8.
P45446 RORB_RAT Nuclear receptor ROR-beta
1k4wA, 1n4hA, 1nq7A.
9.
Q14541 HNF4G_HUMAN Hepatocyte nuclear factor 4-gamma
1lv2A.
10.
P41235 HNF4A_HUMAN Hepatocyte nuclear factor 4-alpha
1pzlA, 3cbbA, 3fs1A, 4b7wA, 4iqrA.
 
P22449 HNF4A_RAT Hepatocyte nuclear factor 4-alpha
1m7wA.
11.
P10827 THA_HUMAN Thyroid hormone receptor alpha
1navA, 2h77A, 2h79A, 3hzfA, 3ilzA, 3jzbA, 4lnwA, 4lnxA.
12.
P06537 GCR_MOUSE Glucocorticoid receptor
3mneA, 3mnoA, 3mnpA.
 
P04150 GCR_HUMAN Glucocorticoid receptor
1m2zA, 1nhzA, 1p93A, 3bqdA, 3cldA, 3e7cA, 3h52A, 3k22A, 3k23A, 4csjA, 4hn5A, 4hn6A, 4lsjA, 4p6wA, 4p6xA.
13.
P06401 PRGR_HUMAN Progesterone receptor
1a28A, 1e3kA, 1sqnA, 1sr7A, 1zucB, 2c7aA, 2ovhA, 2ovmA, 2w8yA, 3d90A, 3g8nA, 3g8oA, 3hq5A, 3kbaA, 3zr7A, 3zraA, 3zrbA, 4a2jA, 4apuA.
14.
P15207 ANDR_RAT Androgen receptor
1i37A, 1i38A, 1r4iA, 1xnnA, 2ihqA, 2nw4A, 3g0wA.
 
P19091 ANDR_MOUSE Androgen receptor
2qpyA.
15.
P28700 RXRA_MOUSE Retinoic acid receptor RXR-alpha
1dkfA, 1xdkA, 3a9eA.
 
P48443 RXRG_HUMAN Retinoic acid receptor RXR-gamma
2gl8A.
 
P19793 RXRA_HUMAN Retinoic acid receptor RXR-alpha
1by4A, 1dszB, 1fbyA, 1fm6A, 1fm9A, 1g1uA, 1g5yA, 1k74A, 1lbdA, 1mv9A, 1mvcA, 1mznA, 1r0nA, 1rdtA, 1rxrA, 1xlsA, 1xv9A, 1xvpA, 1ynwB, 2aclA, 2nllA, 2p1tA, 2p1uA, 2p1vA, 2zxzA, 2zy0A, 3dzuA, 3dzyA, 3e00A, 3e94A, 3falA, 3fc6A, 3fugA, 3h0aA, 3kwyA, 3nspA, 3nsqA, 3oapA, 3ozjA, 3pcuA, 3r29A, 3r2aA, 3r5mA, 3uvvB, 4j5wC, 4k4jA, 4k6iA, 4m8eA, 4m8hA, 4n5gA, 4n8rA, 4nqaA, 4pohA, 4pojA, 4pp3A, 4pp5A.
16.
Q92731 ESR2_HUMAN Estrogen receptor beta
1l2jA, 1ndeA, 1qkmA, 1u3qA, 1u3rA, 1u3sA, 1u9eA, 1x76A, 1x78A, 1x7bA, 1x7jA, 1yy4A, 1yyeA, 1zafA, 2fszA, 2giuA, 2i0gA, 2jj3A, 2nv7A, 2qtuA, 2yjdA, 2ylyA, 2z4bA, 3ollA, 3olsA, 3omoA, 3ompA, 3omqA, 4j24A, 4j26A.
 
Q62986 ESR2_RAT Estrogen receptor beta
1hj1A, 1qknA, 2j7xA, 2j7yA.
17.
P37231 PPARG_HUMAN Peroxisome proliferator-activated receptor gamma
1fm6D, 1fm9D, 1i7iA, 1k74D, 1knuA, 1nyxA, 1prgA, 1rdtD, 1wm0X, 1zeoA, 1zgyA, 2athA, 2f4bA, 2fvjA, 2g0gA, 2g0hA, 2gtkA, 2hfpA, 2hwqA, 2hwrA, 2i4jA, 2i4pA, 2i4zA, 2om9A, 2p4yA, 2pobA, 2prgA, 2q59A, 2q5pA, 2q5sA, 2q61A, 2q6rA, 2q6sA, 2q8sA, 2qmvA, 2vsrA, 2vstA, 2vv0A, 2vv1A, 2vv2A, 2vv3A, 2vv4A, 2xkwA, 2yfeA, 2zk0A, 2zk1A, 2zk2A, 2zk3A, 2zk4A, 2zk5A, 2zk6A, 2znoA, 2zvtA, 3adsA, 3adtA, 3aduA, 3advA, 3adwA, 3adxA, 3an3A, 3an4A, 3b0qA, 3b0rA, 3b1mA, 3b3kA, 3bc5A, 3cdpA, 3cdsA, 3cs8A, 3cwdA, 3d6dA, 3dzuD, 3dzyD, 3e00D, 3et0A, 3et3A, 3fejA, 3furA, 3g9eA, 3gbkA, 3h0aD, 3ho0A, 3hodA, 3ia6A, 3k8sA, 3kmgA, 3lmpA, 3noaA, 3osiA, 3oswA, 3pbaA, 3po9A, 3prgA, 3qt0A, 3r5nA, 3r8aA, 3r8iA, 3s9sA, 3sz1A, 3t03A, 3ty0A, 3u9qA, 3v9tA, 3v9vA, 3v9yA, 3vjhA, 3vjiA, 3vn2A, 3vsoA, 3vspA, 4a4vA, 4a4wA, 4e4kA, 4e4qA, 4em9A, 4emaA, 4f9mA, 4fgyA, 4heeX, 4jazA, 4jl4A, 4l96A, 4l98A, 4o8fA, 4prgA.
18.
P10589 COT1_HUMAN COUP transcription factor 1
2eblA.
19.
P06536 GCR_RAT Glucocorticoid receptor
1gdcA, 1gluA, 1latA, 1r4oA, 1r4rA, 1rgdA, 2gdaA, 3fylA, 3g6pA, 3g6qB, 3g6rB, 3g6tA, 3g6uA, 3g8uA, 3g8xA, 3g97B, 3g99A, 3g9iA, 3g9jA, 3g9mA, 3g9oB, 3g9pB.
20.
P03372 ESR1_HUMAN Estrogen receptor
1a52A, 1ereA, 1errA, 1g50A, 1gwqA, 1gwrA, 1hcpA, 1hcqA, 1l2iA, 1pcgA, 1qktA, 1qkuA, 1r5kA, 1sj0A, 1uomA, 1x7eA, 1x7rA, 1xp1A, 1xp6A, 1xp9A, 1xpcA, 1xqcA, 1yimA, 1yinA, 1zkyA, 2ayrA, 2b1vA, 2b1zA, 2b23A, 2bj4A, 2erdA, 2faiA, 2g44A, 2g5oA, 2i0jA, 2iogA, 2iokA, 2jf9A, 2jfaA, 2lloB, 2llqB, 2ocfA, 2ouzA, 2p15A, 2pogA, 2q6jA, 2q70A, 2qa6A, 2qa8A, 2qabA, 2qe4A, 2qgtA, 2qgwA, 2qh6A, 2qr9A, 2qseA, 2qxmA, 2qxsA, 2qzoA, 2r6wA, 2r6yA, 2yatA, 2yjaB, 3dt3A, 3erdA, 3ertA, 3hlvA, 3hm1A, 3l03A, 3os8A, 3os9A, 3osaA, 3q95A, 3q97A, 3uu7A, 3uuaA, 3uucA, 3uudA, 4aa6A, 4dmaA, 4iu7A, 4iuiA, 4iv2A, 4iv4A, 4ivwA, 4ivyA, 4iw6A, 4iw8A, 4iwcA, 4iwfA, 4pp6A, 4pppA, 4ppsA.
21.
P10275 ANDR_HUMAN Androgen receptor
1e3gA, 1gs4A, 1t5zA, 1t63A, 1t65A, 1xj7A, 1xowA, 1xq2A, 1xq3A, 1z95A, 2am9A, 2amaA, 2ambA, 2ao6A, 2ax6A, 2ax7A, 2ax8A, 2ax9A, 2axaA, 2hvcA, 2oz7A, 2pioA, 2pipL, 2piqA, 2pirA, 2pitA, 2piuA, 2pivA, 2piwA, 2pixA, 2pklA, 2pnuA, 2q7iA, 2q7jA, 2q7kA, 2q7lA, 2yhdA, 2yloA, 2ylpA, 2ylqA, 2z4jA, 3b5rA, 3b65A, 3b66A, 3b67A, 3b68A, 3btrB, 3l3xA, 3l3zA, 3rljA, 3rllA, 3v49A, 3v4aA, 3zqtA, 4hlwA, 4k7aA.
 
O97775 ANDR_PANTR Androgen receptor
1t73A, 1t74A, 1t76A, 1t79A, 1t7fA, 1t7mA, 1t7rA, 1t7tA.
22.
P49869 HR38_DROME Probable nuclear hormone receptor HR38
1pduA.
23.
Q61066 NR0B1_MOUSE Nuclear receptor subfamily 0 group B member 1
3f5cB.

List of Pfam domains

  Pfam code Pfam id Description
PF00104 Hormone_recep Ligand-binding domain of nuclear hormone receptor
PF00105 zf-C4 Zinc finger, C4 type (two domains)
PF02155 GCR Glucocorticoid receptor
PF02159 Oest_recep Oestrogen receptor
PF02161 Prog_receptor Progesterone receptor
PF02166 Androgen_recep Androgen receptor
PF11825 Nuc_recep-AF1 Nuclear/hormone receptor activator site AF-1
PF12497 ERbeta_N Estrogen receptor beta
PF12577 PPARgamma_N PPAR gamma N-terminal region
PF12743 ESR1_C Oestrogen-type nuclear receptor final C-terminal
PF14046 NR_Repeat Nuclear receptor repeat
PB002234
PB008275
PB008491
PB014430
PB014664
PB017573
PB021689
PB027599
PB027874
PB029506
PB030699
PB068171
PB079615
PB107218
PB117795

 

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