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Pfam domain PF00076

Pfam domain PF00076

Pfam domain:   
  PF00076 - RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)  

Below is the list of protein structures in the PDB containing Pfam domain PF00076.

+/- Key to table

Structures in the PDB containing this domain: 413

  Pfam domain
architecture
UniProt
accession
UniProt id Protein name PDB structures
1.
D6PZY5 D6PZY5_TOBAC RNA-binding glycine-rich protein
4c7qA.
 
Q01130 SRSF2_HUMAN Serine/arginine-rich splicing factor 2
2kn4A, 2leaA, 2lebA, 2lecA.
 
Q86U42 PABP2_HUMAN Polyadenylate-binding protein 2
3b4dA, 3ucgA.
 
Q86YN6 PRGC2_HUMAN Peroxisome proliferator-activated receptor gamma coactivator 1-beta
3sp6B.
 
G3LUH8 G3LUH8_CITSI Poly(A)-binding protein 1
2m70A.
 
Q9Y3B4 SF3B6_HUMAN Splicing factor 3B subunit 6
2f9dA, 2f9jA, 2fhoB, 3lqvA.
 
Q9NW64 RBM22_HUMAN Pre-mRNA-splicing factor RBM22
2ytcA.
 
Q9V535 RBM8A_DROME RNA-binding protein 8A
1hl6A, 1oo0B, 1rk8A, 2x1gA.
 
Q9H0Z9 RBM38_HUMAN RNA-binding protein 38
2cqdA.
 
Q12046 CWC2_YEAST Pre-mRNA-splicing factor CWC2
3tp2A, 3u1lA, 3u1mA.
 
P62995 TRA2B_HUMAN Transformer-2 protein homolog beta
2cqcA, 2kxnB, 2rrbA.
 
Q9UKM9 RALY_HUMAN RNA-binding protein Raly
1wf1A.
 
P52298 NCBP2_HUMAN Nuclear cap-binding protein subunit 2
1h2tZ, 1h2vZ, 1h6kX, 1n54B, 3fexB, 3feyB.
 
Q14011 CIRBP_HUMAN Cold-inducible RNA-binding protein
1x5sA.
 
Q9WUK2 IF4H_MOUSE Eukaryotic translation initiation factor 4H
2dngA.
 
P07910 HNRPC_HUMAN Heterogeneous nuclear ribonucleoproteins C1/C2
1txpA, 1wf2A.
 
Q6TY21 EPA2B_XENLA Embryonic polyadenylate-binding protein 2-B
2jwnA.
 
Q3U781 Q3U781_MOUSE MCG21131, isoform CRA_a
2i2yA.
 
P57052 RBM11_HUMAN Splicing regulator RBM11
2ywkA.
 
O25501 O25501_HELPY Ss-DNA binding protein 12RNP2
2ki2A.
 
Q8N1H4 Q8N1H4_HUMAN cDNA FLJ40872 fis, clone TUTER2000283, highly similar to Homo sapiens transformer-2-beta (SFRS10) gene
2rraA.
 
Q9Y5S9 RBM8A_HUMAN RNA-binding protein 8A
2hyiB, 2j0qD, 2j0sD, 2xb2D, 3ex7B.
 
P18615 NELFE_HUMAN Negative elongation factor E
1x5pA, 2bz2A, 2jx2A.
2.
Q8NE35 CPEB3_HUMAN Cytoplasmic polyadenylation element-binding protein 3
2dnlA.
3.
Q9UBK2 PRGC1_HUMAN Peroxisome proliferator-activated receptor gamma coactivator 1-alpha
3b1mB, 3cs8B, 3d24B, 3v9vC.
4.
Q96IZ5 RBM41_HUMAN RNA-binding protein 41
2cpxA.
5.
P38996 NAB3_YEAST Nuclear polyadenylated RNA-binding protein 3
2kviA, 2l41A, 2xnqA, 2xnrA.
6.
Q16629 SRSF7_HUMAN Serine/arginine-rich splicing factor 7
2hvzA.
7.
P84103 SRSF3_HUMAN Serine/arginine-rich splicing factor 3
2i38A.
8.
Q64368 DAZL_MOUSE Deleted in azoospermia-like
2xs2A, 2xs7A, 2xsfA.
9.
P09651 ROA1_HUMAN Heterogeneous nuclear ribonucleoprotein A1
1ha1A, 1l3kA, 1pgzA, 1po6A, 1u1kA, 1u1lA, 1u1mA, 1u1nA, 1u1oA, 1u1pA, 1u1qA, 1u1rA, 1up1A, 2h4mC, 2lyvA, 2up1A.
 
Q9D0B0 SRSF9_MOUSE Serine/arginine-rich splicing factor 9
1wg4A.
 
Q921F2 TADBP_MOUSE TAR DNA-binding protein 43
3d2wA.
 
Q13148 TADBP_HUMAN TAR DNA-binding protein 43
1wf0A, 2cqgA, 4bs2A, 4iufA.
 
Q9NX07 TSAP1_HUMAN tRNA selenocysteine 1-associated protein 1
2dhgA, 2divA.
 
P09012 SNRPA_HUMAN U1 small nuclear ribonucleoprotein A
1audA, 1cx0A, 1drzA, 1dz5A, 1fhtA, 1hp6C, 1m5kC, 1m5oC, 1m5pC, 1m5vC, 1nrcA, 1nu4A, 1numA, 1sj3P, 1sj4P, 1sjfA, 1t42A, 1u6bA, 1urnA, 1vbxA, 1vbyA, 1vbzA, 1vc0A, 1vc5A, 1vc6A, 1vc7A, 1zznA, 2a3jA, 2nz4A, 2oihA, 2oj3A, 2u1aA, 3bo2A, 3bo3A, 3bo4A, 3culA, 3cunA, 3egzA, 3g8sA, 3g95A, 3g9cA, 3hhnB, 3iinA, 3irwP, 3iwnC, 3k0jA, 3mumP, 3murP, 3mutP, 3muvP, 3mxhP, 3p49B, 3pgwA, 3r1hA, 3r1lA, 3ucuP, 3uczP, 3ud3P, 3ud4P, 3utrB, 4c4wA.
 
Q96LT9 RBM40_HUMAN RNA-binding protein 40
3egnA.
 
Q15434 RBMS2_HUMAN RNA-binding motif, single-stranded-interacting protein 2
1x4eA.
 
Q15427 SF3B4_HUMAN Splicing factor 3B subunit 4
1x5tA, 1x5uA.
 
Q61474 MSI1H_MOUSE RNA-binding protein Musashi homolog 1
1uawA, 2mssA, 2mstA, 2rs2A.
 
P19339 SXL_DROME Protein sex-lethal
1b7fA, 1sxlA, 2sxlA, 3sxlA.
 
Q96EP5 DAZP1_HUMAN DAZ-associated protein 1
2dgsA, 2dh8A.
 
P43332 SNRPA_DROME U1 small nuclear ribonucleoprotein A
2aymA, 2b0gA, 2fjjA, 2k3kA.
 
Q01560 NOP3_YEAST Nucleolar protein 3
2jvoA, 2jvrA, 2osqA, 2osrA.
 
Q9UHX1 PUF60_HUMAN Poly(U)-binding-splicing factor PUF60
2kxfA, 2kxhA, 3dxbA, 3ue2A, 3us5A, 3uwtA.
10.
Q8TBF4 ZCRB1_HUMAN Zinc finger CCHC-type and RNA-binding motif-containing protein 1
2e5hA.
11.
Q26548 PPIE_SCHMA Peptidyl-prolyl cis-trans isomerase E (E.C. 5.2.1.8)
2ck1A, 2cmtA.
 
Q9UNP9 PPIE_HUMAN Peptidyl-prolyl cis-trans isomerase E (E.C. 5.2.1.8)
1zcxA, 1zmfA, 2cqbA, 2ku7A, 2kyxA, 2r99A, 3lpyA, 3mdfA, 3uchA.
12.
P49756 RBM25_HUMAN RNA-binding protein 25
3v53A.
13.
P38159 RBMX_HUMAN RNA-binding motif protein, X chromosome
2mb0B, 2mksA.
 
P0DJD3 RBY1A_HUMAN RNA-binding motif protein, Y chromosome, family 1 member A1
2fy1A.
14.
Q9BYG3 MK67I_HUMAN MKI67 FHA domain-interacting nucleolar phosphoprotein
2affB.
15.
O43251 RFOX2_HUMAN RNA binding protein fox-1 homolog 2
2cq3A.
 
Q9NWB1 RFOX1_HUMAN RNA binding protein fox-1 homolog 1
2errA.
16.
Q86V81 THOC4_HUMAN THO complex subunit 4
3ulhA.
 
O08583 THOC4_MOUSE THO complex subunit 4
1no8A.
17.
Q2M296 MTHSD_HUMAN Methenyltetrahydrofolate synthase domain-containing protein
2e5jA.
18.
Q13283 G3BP1_HUMAN Ras GTPase-activating protein-binding protein 1 (E.C. 3.6.4.12, 3.6.4.13)
3q90A.
19.
Q9NIH4 Q9NIH4_9TRYP RNA binding protein La-like protein
1s29A.
20.
P08621 RU17_HUMAN U1 small nuclear ribonucleoprotein 70 kDa
2l5iA, 2l5jA, 3cw1K, 3pgwS.
21.
O75821 EIF3G_HUMAN Eukaryotic translation initiation factor 3 subunit G
2cq0A.
22.
P08579 RU2B_HUMAN U2 small nuclear ribonucleoprotein B''
1a9nB.
23.
P22626 ROA2_HUMAN Heterogeneous nuclear ribonucleoproteins A2/B1
1x4bA.
24.
P23588 IF4B_HUMAN Eukaryotic translation initiation factor 4B
1wi8A, 2j76E.
25.
Q8N684 CPSF7_HUMAN Cleavage and polyadenylation specificity factor subunit 7
3n9uC.
26.
Q967R0 Q967R0_TRYCR RNA-binding protein UBP-1
1u6fA.
27.
P35637 FUS_HUMAN RNA-binding protein FUS
2la6A, 2lcwA, 4fddB, 4fq3B.
28.
P06103 EIF3B_YEAST Eukaryotic translation initiation factor 3 subunit B
3ns5A, 3ns6A, 3zwlE.
29.
P25299 RNA15_YEAST mRNA 3'-end-processing protein RNA15
2km8B, 2l9bA, 2x1aA, 2x1bA, 2x1fA.
30.
Q96PK6 RBM14_HUMAN RNA-binding protein 14
2dnpA.
31.
Q6PDM2 SRSF1_MOUSE Serine/arginine-rich splicing factor 1
1x4cA.
 
Q07955 SRSF1_HUMAN Serine/arginine-rich splicing factor 1
1x4aA, 2m7sA, 2m8dB, 2o3dA, 3begB, 4c0oC.
32.
P29558 RBMS1_HUMAN RNA-binding motif, single-stranded-interacting protein 1
1x5oA.
33.
P55884 EIF3B_HUMAN Eukaryotic translation initiation factor 3 subunit B
2krbA, 2nlwA.
34.
Q6JXI6 Q6JXI6_TETTH Telomerase associated protein p65
2lslA, 4erdA, 4eytA.
35.
P17133 RU17_DROME U1 small nuclear ribonucleoprotein 70 kDa
2bn5B.
36.
Q15717 ELAV1_HUMAN ELAV-like protein 1
3hi9A, 4ed5A, 4eglA, 4fxvA.
 
O95319 CELF2_HUMAN CUGBP Elav-like family member 2
4ljmB, 4lmzA.
 
Q60900 ELAV3_MOUSE ELAV-like protein 3
1d8zA, 1d9aA, 1fnxH.
 
Q96J87 CELF6_HUMAN CUGBP Elav-like family member 6
2dgqA.
 
A0AV96 RBM47_HUMAN RNA-binding protein 47
2disA.
 
Q01085 TIAR_HUMAN Nucleolysin TIAR
1x4gA, 2cqiA, 2dh7A.
 
P26378 ELAV4_HUMAN ELAV-like protein 4
1fxlA, 1g2eA.
 
O60506 HNRPQ_HUMAN Heterogeneous nuclear ribonucleoprotein Q
2dguA.
 
Q92879 CELF1_HUMAN CUGBP Elav-like family member 1
2cpzA, 2dhsA, 2rq4A, 2rqcA, 3nmrA, 3nnaA, 3nncA.
 
O43390 HNRPR_HUMAN Heterogeneous nuclear ribonucleoprotein R
2dk2A.
37.
Q8WXF1 PSPC1_HUMAN Paraspeckle component 1
3sdeA.
38.
P33240 CSTF2_HUMAN Cleavage stimulation factor subunit 2
1p1tA, 2j8pA.
 
Q6CKN2 Q6CKN2_KLULA KLLA0F09383p
4ebaG.
39.
P05455 LA_HUMAN Lupus La protein
1owxA, 1s79A, 1s7aA, 1ytyA, 2vodA, 2vooA, 2vopA.
40.
Q14103 HNRPD_HUMAN Heterogeneous nuclear ribonucleoprotein D0
1hd0A, 1hd1A, 1iqtA, 1wtbA, 1x0fA, 2z5nB.
41.
P26369 U2AF2_MOUSE Splicing factor U2AF 65 kDa subunit
2m52A, 3v4mA.
 
P26368 U2AF2_HUMAN Splicing factor U2AF 65 kDa subunit
1jmtB, 1o0pA, 1opiA, 1u2fA, 2fzrA, 2g4bA, 2hzcA, 2m0gB, 2u2fA, 2yh0A, 2yh1A, 3vafA, 3vagA, 3vahA, 3vaiA, 3vajA, 3vakA, 3valA, 4fxwA.
42.
Q8IY67 RAVR1_HUMAN Ribonucleoprotein PTB-binding 1
3h2vE, 3smzA, 3vf0B.
43.
P53617 NRD1_YEAST Protein NRD1
2m88A, 3cljA.
44.
Q99383 HRP1_YEAST Nuclear polyadenylated RNA-binding protein 4
2cjkA, 2km8C.
45.
Q86U06 RBM23_HUMAN Probable RNA-binding protein 23
2cq4A, 2dnzA.
46.
Q15020 SART3_HUMAN Squamous cell carcinoma antigen recognized by T-cells 3
2do4A.
47.
Q6PHZ5 RB15B_MOUSE Putative RNA-binding protein 15B
1whyA.
48.
P32588 PUB1_YEAST Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1
2la4A, 3md1A, 3md3A.
49.
P52912 TIA1_MOUSE Nucleolysin TIA-1
2dgoA, 2rneA.
 
P31483 TIA1_HUMAN Nucleolysin TIA-1 isoform p40
2mjnA, 3bs9A.
50.
Q9BQ04 RBM4B_HUMAN RNA-binding protein 4B
2dgtA.
 
Q9BWF3 RBM4_HUMAN RNA-binding protein 4
2dnqA.
51.
Q15233 NONO_HUMAN Non-POU domain-containing octamer-binding protein
3sdeB.
52.
Q9C5J3 Q9C5J3_ARATH Putative uncharacterized protein At5g25060
2e62A.
53.
Q9HCJ3 RAVR2_HUMAN Ribonucleoprotein PTB-binding 2
1wg1A.
54.
P49960 PRP24_YEAST U4/U6 snRNA-associated-splicing factor PRP24
2go9A, 2kh9A, 2l9wA, 4n0tA.
55.
Q9NQ94 A1CF_HUMAN APOBEC1 complementation factor
2cpdA.
56.
P26599 PTBP1_HUMAN Polypyrimidine tract-binding protein 1
1qm9A, 1sjqA, 1sjrA, 2ad9A, 2adbA, 2adcA, 2evzA, 3zzzA.
57.
P52597 HNRPF_HUMAN Heterogeneous nuclear ribonucleoprotein F
2hglA, 2hgnA, 2kfyA, 2kg0A, 2kg1A.
 
Q9Z2X1 HNRPF_MOUSE Heterogeneous nuclear ribonucleoprotein F
2db1A.
58.
Q9UPN6 SCAF8_HUMAN Protein SCAF8
2diwA, 3d9jA, 3d9kA, 3d9lA, 3d9mA, 3d9oA.
59.
Q99K48 NONO_MOUSE Non-POU domain-containing octamer-binding protein
2cpjA, 2rs8A.
60.
O18409 O18409_DROME Testis-specific RNP-type RNA binding protein
2khcA.
61.
P08199 NUCL_MESAU Nucleolin
1fj7A, 1fjcA, 1fjeB, 1rkjA.
 
P19338 NUCL_HUMAN Nucleolin
2fc8A, 2fc9A, 2krrA.
62.
Q09702 NRD1_SCHPO Negative regulator of differentiation 1
2rt3A.
63.
Q8CGC6 RBM28_MOUSE RNA-binding protein 28
1x4hA.
64.
Q27335 Q27335_TRYCR Poly(A) binding protein
1nmrA.
 
Q9H361 PABP3_HUMAN Polyadenylate-binding protein 3
4iveA.
 
P04147 PABP_YEAST Polyadenylate-binding protein, cytoplasmic and nuclear
1ifwA.
 
P93616 P93616_WHEAT Poly(A)-binding protein
2dydA.
 
P11940 PABP1_HUMAN Polyadenylate-binding protein 1
1cvjA, 1g9lA, 1jgnA, 2k8gA, 2rqgB, 2rqhB, 2x04A, 3ktpA, 3kuiA, 3kujA, 3kurA, 3kusA, 3kutA, 3pknA, 3pthA, 4f02A, 4f25A, 4f26A.
 
Q2VIP3 Q2VIP3_HUMAN PABP3
2d9pA.
65.
Q14498 RBM39_HUMAN RNA-binding protein 39
2jrsA, 2mhnA, 4oz0A, 4oz1A.
 
Q8VH51 RBM39_MOUSE RNA-binding protein 39
2lq5A, 3s6eA.
66.
Q8R4X3 RBM12_MOUSE RNA-binding protein 12
2cqpA.
 
Q9NTZ6 RBM12_HUMAN RNA-binding protein 12
1welA, 2cpyA, 2dnnA, 2ek1A, 2ek6A.
67.
O15047 SET1A_HUMAN Histone-lysine N-methyltransferase SETD1A (E.C. 2.1.1.43)
3s8sA, 3uvnA.
68.
P52272 HNRPM_HUMAN Heterogeneous nuclear ribonucleoprotein M
2dgvA, 2dh9A, 2do0A, 2ot8C.
69.
Q9Y6M1 IF2B2_HUMAN Insulin-like growth factor 2 mRNA-binding protein 2
2cqhA.
70.
Q9Y4C8 RBM19_HUMAN Probable RNA-binding protein 19
2dgwA.
 
Q8R3C6 RBM19_MOUSE Probable RNA-binding protein 19
1whwA, 1whxA, 2cpfA, 2cphA.
71.
Q9NZI8 IF2B1_HUMAN Insulin-like growth factor 2 mRNA-binding protein 1
3krmA.
72.
Q96T58 MINT_HUMAN Msx2-interacting protein
1ow1A, 2rt5A, 4p6qA.

List of Pfam domains

  Pfam code Pfam id Description
PF00076 RRM_1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PF00013 KH_1 KH domain
PF00098 zf-CCHC Zinc knuckle
PF00160 Pro_isomerase Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
PF00641 zf-RanBP Zn-finger in Ran binding protein and others
PF00658 PABP Poly-adenylate binding protein, unique domain
PF00856 SET SET domain
PF01480 PWI PWI domain
PF01805 Surp Surp module
PF01812 5-FTHF_cyc-lig 5-formyltetrahydrofolate cyclo-ligase family
PF02136 NTF2 Nuclear transport factor 2 (NTF2) domain
PF04818 CTD_bind RNA polymerase II-binding domain.
PF05383 La La domain
PF05391 Lsm_interact Lsm interaction motif
PF07744 SPOC SPOC domain
PF08075 NOPS NOPS (NUC059) domain
PF08080 zf-RNPHF RNPHF zinc finger
PF08081 RBM1CTR RBM1CTR (NUC064) family
PF08143 CBFNT CBFNT (NUC161) domain
PF08312 cwf21 cwf21 domain
PF08662 eIF2A Eukaryotic translation initiation factor eIF2A
PF08777 RRM_3 RNA binding motif
PF11532 HnRNP_M Heterogeneous nuclear ribonucleoprotein M
PF11764 N-SET COMPASS (Complex proteins associated with Set1p) component N
PF12196 hNIFK_binding FHA Ki67 binding domain of hNIFK
PF12220 U1snRNP70_N U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
PF12353 eIF3g Eukaryotic translation initiation factor 3 subunit G
PF12414 Fox-1_C Calcitonin gene-related peptide regulator C terminal
PF13865 FoP_duplication C-terminal duplication domain of Friend of PRMT1
PF13893 RRM_5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PF14259 RRM_6 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain)
PF14304 CSTF_C Transcription termination and cleavage factor C-terminal
PF14327 CSTF2_hinge Hinge domain of cleavage stimulation factor subunit 2
PF14709 DND1_DSRM double strand RNA binding domain from DEAD END PROTEIN 1
PF15519 RBM39linker linker between RRM2 and RRM3 domains in RBM39 protein
PB000013
PB000127
PB000181
PB001110
PB001171
PB001253
PB001313
PB001534
PB002209
PB002825
PB003287
PB003776
PB004540
PB005206
PB007114
PB008282
PB008968
PB010161
PB010449
PB010481
PB010726
PB012082
PB012581
PB013504
PB013909
PB016507
PB016701
PB017314
PB017673
PB017985
PB019031
PB019319
PB019752
PB020624
PB021002
PB021248
PB024657
PB024930
PB029905
PB033213
PB041289
PB041492
PB042826
PB044852
PB053519
PB055904
PB065616
PB066528
PB072677
PB081607
PB085223
PB313294
PB329168

 

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