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Pfam domain PF00046

Pfam domain PF00046

Pfam domain:   
  PF00046 - Homeobox domain  

Below is the list of protein structures in the PDB containing Pfam domain PF00046.

+/- Key to table

Structures in the PDB containing this domain: 159

  Pfam domain
architecture
UniProt
accession
UniProt id Protein name PDB structures
1.
Q9H9S0 NANOG_HUMAN Homeobox protein NANOG
2kt0A.
 
P52952 NKX25_HUMAN Homeobox protein Nkx-2.5
3rkqA.
 
O43763 TLX2_HUMAN T-cell leukemia homeobox protein 2
3a03A.
 
Q03014 HHEX_HUMAN Hematopoietically-expressed homeobox protein HHEX
1wqiA, 2e1oA.
 
P83949 UBX_DROME Homeotic protein ultrabithorax
1b8iA.
 
P09081 BCD_DROME Homeotic protein bicoid
1zq3P.
 
P13297 MSX1_MOUSE Homeobox protein MSX-1
1ig7A.
 
Q14549 GBX1_HUMAN Homeobox protein GBX-1
2m34A, 2me6A.
 
P56915 GSC_HUMAN Homeobox protein goosecoid
2dmuA.
 
Q8R1H0 HOP_MOUSE Homeodomain-only protein
1uhsA, 2hi3A.
 
P70118 PDX1_MESAU Pancreas/duodenum homeobox protein 1
2h1kA.
 
Q9UBX0 HESX1_HUMAN Homeobox expressed in ES cells 1
2k40A.
 
P14653 HXB1_HUMAN Homeobox protein Hox-B1
1b72A.
 
P06602 EVE_DROME Segmentation protein even-skipped
1jggA.
 
Q80Z64 NANOG_MOUSE Homeobox protein NANOG
2vi6A.
 
Q15475 SIX1_HUMAN Homeobox protein SIX1
4egcA.
 
P23441 NKX21_RAT Homeobox protein Nkx-2.1
1fttA.
 
Q99801 NKX31_HUMAN Homeobox protein Nkx-3.1
2l9rA.
2.
Q7Z353 HDX_HUMAN Highly divergent homeobox
2da4A.
3.
P22808 VND_DROME Homeobox protein vnd
1nk2P, 1nk3P, 1qryA, 1vndA.
4.
Q7KSY7 Q7KSY7_DROME Antennapedia, isoform G
2hoaA.
 
P02833 ANTP_DROME Homeotic protein antennapedia
1ahdP, 1homA, 1kz0A, 1kz5A, 1omqA, 1sanA, 9antA.
5.
Q9HBU1 BARX1_HUMAN Homeobox protein BarH-like 1
2dmtA.
6.
P09077 SCR_DROME Homeotic protein Sex combs reduced
2r5yA, 2r5zA.
7.
P0CY08 MTAL2_YEAST Mating-type protein ALPHA2
1akhB, 1aplC, 1k61A, 1le8B, 1mnmC, 1yrnB.
8.
P0CY10 MATA1_YEASX Mating-type protein A1
1akhA, 1f43A, 1le8A, 1mh3A, 1mh4A, 1yrnA.
9.
P09089 ZEN1_DROME Protein zerknuellt 1
1kz2A.
10.
Q26602 SMOX3_SCHMA Homeobox protein SMOX-3
2al9A.
11.
Q8VD35 Q8VD35_MOUSE Homeobox protein OTX2
2dmsA.
12.
Q06453 AL_DROME Homeobox protein aristaless
3a01B, 3a02A, 3lnqA.
 
Q99697 PITX2_HUMAN Pituitary homeobox 2
1yz8P, 2l7fP, 2l7mP, 2lkxA.
13.
Q05917 HME2_CHICK Homeobox protein engrailed-2
3zobA.
14.
P09086 PO2F2_HUMAN POU domain, class 2, transcription factor 2
1hdpA.
 
P10037 PIT1_RAT Pituitary-specific positive transcription factor 1
1au7A.
 
P21952 PO3F1_MOUSE POU domain, class 3, transcription factor 1
2xsdC.
 
Q14863 PO6F1_HUMAN POU domain, class 6, transcription factor 1
3d1nI.
 
P14859 PO2F1_HUMAN POU domain, class 2, transcription factor 1
1cqtA, 1e3oC, 1gt0C, 1hf0A, 1o4xA, 1octC, 1pogA, 1pouA.
15.
P26367 PAX6_HUMAN Paired box protein Pax-6
2cueA, 6paxA.
 
P06601 PRD_DROME Segmentation protein paired
1fjlA, 1pdnC.
16.
A4II00 A4II00_XENTR One cut domain family member
2d5vA.
 
O08755 HNF6_MOUSE Hepatocyte nuclear factor 6
1s7eA.
17.
P40427 EXD_DROME Homeobox protein extradenticle
1b8iB, 2r5yB, 2r5zB.
18.
P09631 HXA9_MOUSE Homeobox protein Hox-A9
1pufA.
 
P31274 HXC9_HUMAN Homeobox protein Hox-C9
2lp0A.
19.
Q6NT76 HMBX1_HUMAN Homeobox-containing protein 1
2cufA, 4j19A.
20.
Q92826 HXB13_HUMAN Homeobox protein Hox-B13
2craA.
21.
Q9VD99 Q9VD99_DROME Homeodomain-containing protein
3a01A.
22.
P20263 PO5F1_MOUSE POU domain, class 5, transcription factor 1
1ocpA, 3l1pA.
23.
P02836 HMEN_DROME Segmentation polarity homeobox protein engrailed
1du0A, 1enhA, 1hddC, 1p7iA, 1p7jA, 1ztrA, 2hddA, 2hosA, 2hotA, 2jwtA, 2p81A, 3hddA.
24.
Q8C172 CERS6_MOUSE Ceramide synthase 6
1x2mA.
25.
Q9H161 ALX4_HUMAN Homeobox protein aristaless-like 4
2m0cA.
26.
P41778 PBX1_MOUSE Pre-B-cell leukemia transcription factor 1
1du6A, 1lfuP.
 
P40424 PBX1_HUMAN Pre-B-cell leukemia transcription factor 1
1b72B, 1pufB.
27.
P02835 FTZ_DROME Segmentation protein fushi tarazu
1ftzA.
28.
P56178 DLX5_HUMAN Homeobox protein DLX-5
2djnA.
29.
P23760 PAX3_HUMAN Paired box protein Pax-3
3cmyA.
30.
P50481 LHX3_MOUSE LIM/homeobox protein Lhx3
2rgtA.
 
Q9NQ69 LHX9_HUMAN LIM/homeobox protein Lhx9
2dmqA.
 
Q9CXV0 ISL2_MOUSE Insulin gene enhancer protein ISL-2
3mmkA.
 
A2ALD9 A2ALD9_MOUSE Lhx3 protein
2jtnA.
 
P50480 ISL2_RAT Insulin gene enhancer protein ISL-2
1bw5A.
 
P61372 ISL1_MOUSE Insulin gene enhancer protein ISL-1
2rgtA, 4jcjA.
31.
P35680 HNF1B_HUMAN Hepatocyte nuclear factor 1-beta
2da6A, 2h8rA.
32.
Q62424 HXA13_MOUSE Homeobox protein Hox-A13
2ld5A.
 
P31271 HXA13_HUMAN Homeobox protein Hox-A13
2l7zA.
33.
Q9D6K9 CERS5_MOUSE Ceramide synthase 5 (E.C. 2.3.1.24)
2cqxA.
34.
Q9UPW6 SATB2_HUMAN DNA-binding protein SATB2
1wi3A, 1wizA, 2csfA.
35.
Q01826 SATB1_HUMAN DNA-binding protein SATB1
1yseA, 2l1pA, 2o49A, 2o4aA, 3nzlA, 3tuoA.
36.
Q9H4I2 ZHX3_HUMAN Zinc fingers and homeoboxes protein 3
2da5A, 2dn0A.
37.
P22361 HNF1A_MOUSE Hepatocyte nuclear factor 1-alpha
1f93E, 1g2yA, 1g2zA, 1g39A, 1jb6A.
 
P15257 HNF1A_RAT Hepatocyte nuclear factor 1-alpha
1lfbA, 2lfbA.
 
P20823 HNF1A_HUMAN Hepatocyte nuclear factor 1-alpha
1dt8A, 1ic8A, 2gypA.
38.
P53776 LHX4_MOUSE LIM/homeobox protein Lhx4
3mmkA.
39.
O14529 CUX2_HUMAN Homeobox protein cut-like 2
1wh6A, 1wh8A, 1x2lA.
40.
Q9Y6X8 ZHX2_HUMAN Zinc fingers and homeoboxes protein 2
2dmpA, 3nauA.
41.
Q9UKY1 ZHX1_HUMAN Zinc fingers and homeoboxes protein 1
2djoA, 2ecbA, 2ghfA, 2ly9A, 3narA.
42.
P37275 ZEB1_HUMAN Zinc finger E-box-binding homeobox 1
2e19A.
43.
Q9JJN2 ZFHX4_MOUSE Zinc finger homeobox protein 4
2yrkA.
44.
Q15911 ZFHX3_HUMAN Zinc finger homeobox protein 3
2da1A, 2da2A, 2da3A.

List of Pfam domains

  Pfam code Pfam id Description
PF00046 Homeobox Homeobox domain
PF00096 zf-C2H2 Zinc finger, C2H2 type
PF00157 Pou Pou domain - N-terminal to homeobox domain
PF00292 PAX 'Paired box' domain
PF00412 LIM LIM domain
PF02376 CUT CUT domain
PF03529 TF_Otx Otx1 transcription factor
PF03792 PBC PBC domain
PF03798 TRAM_LAG1_CLN8 TLC domain
PF03826 OAR OAR domain
PF03867 FTZ Fushi tarazu (FTZ), N-terminal region
PF04617 Hox9_act Hox9 activation region
PF04812 HNF-1B_C Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus
PF04813 HNF-1A_C Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus
PF04814 HNF-1_N Hepatocyte nuclear factor 1 (HNF-1), N terminus
PF05605 zf-Di19 Drought induced 19 protein (Di19), zinc-binding
PF10525 Engrail_1_C_sig Engrailed homeobox C-terminal signature domain
PF11569 Homez Homeodomain leucine-zipper encoding, Homez
PF12284 HoxA13_N Hox protein A13 N terminal
PF12360 Pax7 Paired box protein 7
PF12413 DLL_N Homeobox protein distal-less-like N terminal
PF12874 zf-met Zinc-finger of C2H2 type
PF13465 zf-H2C2_2 Zinc-finger double domain
PF13909 zf-H2C2_5 C2H2-type zinc-finger domain
PB001229
PB001938
PB002537
PB002819
PB004948
PB004963
PB005410
PB005782
PB007416
PB007665
PB008011
PB008103
PB009146
PB010008
PB012595
PB013015
PB014864
PB015281
PB015354
PB016065
PB017297
PB019013
PB019714
PB021561
PB021599
PB022595
PB023941
PB027798
PB030019
PB031852
PB037031
PB037403
PB040272
PB041272
PB054865
PB055924
PB058397
PB058542
PB060629
PB063733
PB076306
PB100651
PB118253
PB338108

 

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