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Protein-protein interfaces page

Protein-protein interactions shown in PDBsum are:
  • Hydrogen bonds
  • Non-bonded contacts
  • Salt bridges
  • Disulphide bonds
Hydrogen bonds and non-bonded contacts are calculated by HBPLUS. Details of its calculations are given in:
https://www.ebi.ac.uk/thornton-srv/software/HBPLUS/manual.html
Also shown are salt bridges, computed using the definition in:
Kumar & Nussinov (1999). J.Mol.Biol., 293, 1241-1255
Interface areas are computed using a program called NACCESS:
http://wolf.bms.umist.ac.uk/naccess
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