PDBsum entry 8rkf

Cell adhesion

PDB id: 8rkf

Contents

Protein chains

208 a.a.

194 a.a.

Ligands

NAG ×6

PDB id:

8rkf

Name:

Cell adhesion

Title:

Crystal structure of the zp-n1 and zp-n2 domains of human zp2 (hzp2- n1n2)

Structure:

Zona pellucida sperm-binding protein 2. Chain: a, b. Synonym: zona pellucida glycoprotein 2,zp-2,zona pellucida protein a. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Organ: ovary. Gene: zp2, zpa. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293s. Expression_system_atcc_number: crl-3022.

Resolution:

3.20Å R-factor: 0.240 R-free: 0.293

Authors:

E.Dioguardi,A.Stsiapanava,D.De Sanctis,L.Jovine

Key ref:

S.Nishio et al. Zp2 cleavage blocks polyspermy by modulating the architecture of the egg coat. Cell(cambridge,Mass ), . PubMed id: 38490181

Date:

25-Dec-23 Release date: 13-Mar-24

Protein chain

Q05996  (ZP2_HUMAN) -  Zona pellucida sperm-binding protein 2 from Homo sapiens

Seq: 745 a.a.

Struc: 208 a.a.*

Protein chain

Q05996  (ZP2_HUMAN) -  Zona pellucida sperm-binding protein 2 from Homo sapiens

Seq: 745 a.a.

Struc: 194 a.a.

* PDB and UniProt seqs differ at 5 residue positions (black crosses)