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PDBsum entry 7mw2

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protein ligands Protein-protein interface(s) links
Viral protein/immune system PDB id
7mw2

 

 

 

 

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Contents
Protein chains
1004 a.a.
215 a.a.
212 a.a.
Ligands
NAG-NAG ×21
NAG ×30
PDB id:
7mw2
Name: Viral protein/immune system
Title: Structure of the sars-cov-2 spike trimer with all rbds down in complex with the fab fragment of human neutralizing antibody clone 6
Structure: Spike glycoprotein. Chain: a, c, b. Synonym: s glycoprotein, e2, peplomer protein. Engineered: yes. Fab of antibody clone 6, light chain. Chain: e, l, g. Engineered: yes. Fab of antibody clone 6, heavy chain. Chain: d, h, f.
Source: Severe acute respiratory syndrome coronavirus 2. Organism_taxid: 2697049. Gene: s, 2. Expressed in: mammalian expression vector pcdna3.1-flag. Expression_system_taxid: 1944925. Homo sapiens. Human. Organism_taxid: 9606.
Authors: Y.Hu,Y.Xiong
Key ref: Y.Hu and y.xiong Development, Structure and function of potent monospe and bispecific monoclonal antibodies that neutralize sars-Cov-2 and its mutant variant. To be published, . PubMed id: 35347138
Date:
15-May-21     Release date:   16-Mar-22    
PROCHECK
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 Headers
 References

Protein chains
P0DTC2  (SPIKE_SARS2) -  Spike glycoprotein from Severe acute respiratory syndrome coronavirus 2
Seq:
Struc:
 
Seq:
Struc:
 
Seq:
Struc:
1273 a.a.
1004 a.a.*
Protein chains
No UniProt id for this chain
Struc: 215 a.a.
Protein chains
No UniProt id for this chain
Struc: 212 a.a.
Key:    PfamA domain  Secondary structure
* PDB and UniProt seqs differ at 2 residue positions (black crosses)

 

 

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