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UniProt functional annotation for P25441 | ||
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| UniProt code: P25441. |
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| Organism: | |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). |
| Taxonomy: | |
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces. |
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| Function: | |
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Essential for tRNA synthesis. The RPC53/RPC4-RPC37/RPC5 subcomplex is required for terminator recognition and reinitiation. {ECO:0000269|PubMed:16362040}. |
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| Subunit: | |
Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits. Interacts with RPC37/RPC5. RPC53/RPC4, RPC37/RPC5 and RPC11/RPC10 probably form a Pol III subcomplex. {ECO:0000269|PubMed:10393904}. |
| Subcellular location: | |
Nucleus {ECO:0000269|PubMed:14562095}. |
| Miscellaneous: | |
Present with 998 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}. |
| Similarity: | |
Belongs to the eukaryotic RPC4/POLR3D RNA polymerase subunit family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.