|
|
||
|
|
|
|
|
UniProt functional annotation for Q04712 | ||
|
|
|
|
|
|
||
| UniProt code: Q04712. |
|
||
| Organism: | |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). |
| Taxonomy: | |
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces. |
|
||
|
||
| Function: | |
Acts as component of the core factor (CF) complex which is essential for the initiation of rDNA transcription by RNA polymerase I. After binding of UAF (upstream activation factor) to an upstream element of the promoter, CF is recruited in a SPT15/TBP-dependent manner to form a preinitiation complex. {ECO:0000269|PubMed:8887672}. |
|
||
| Subunit: | |
Component of the core factor (CF) complex, which consists of RRN6, RRN7 and RRN11. The CF heterotrimer may further dimerize to form a hexamer. RRN11 interacts with RRN6, RRN7 and SPT15. {ECO:0000269|PubMed:7958901, ECO:0000269|PubMed:8702872}. |
| Subcellular location: | |
Nucleus, nucleolus {ECO:0000269|PubMed:14562095}. |
| Miscellaneous: | |
Present with 476 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}. |
Annotations taken from UniProtKB at the EBI.