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UniProt functional annotation for P03518 | ||
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| UniProt code: P03518. |
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| Organism: | |
Rift valley fever virus (RVFV). |
| Taxonomy: | |
Viruses; Riboviria; Orthornavirae; Negarnaviricota; Polyploviricotina; Ellioviricetes; Bunyavirales; Phenuiviridae; Phlebovirus. |
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| Function: | |
[Glycoprotein N]: interact with each other and are present at the surface of the virion. They are able to attach the virion to a cell receptor and to promote fusion of membranes after endocytosis of the virion (By similarity). {ECO:0000250}. |
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| Function: | |
[Glycoprotein C]: interact with each other and are present at the surface of the virion. Together they play a role in attachment of the virion to a cell receptor. Promotes fusion of membranes after endocytosis of the virion (By similarity). {ECO:0000250}. |
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| Function: | |
[Isoform NSm protein]: Plays a role for virus dissemination in mouse. {ECO:0000250|UniProtKB:P21401}. |
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| Function: | |
[NSm-Gn protein]: Plays a role for virus dissemination in mosquitoes. {ECO:0000250|UniProtKB:P21401}. |
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| Subunit: | |
Glycoprotein C and Glycoprotein N interacts with each other. {ECO:0000250}. |
| Subcellular location: | |
[Glycoprotein N]: Virion membrane {ECO:0000250|UniProtKB:P21401}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:P21401}. Host Golgi apparatus membrane {ECO:0000250|UniProtKB:P21401}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:P21401}. Host endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P21401}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:P21401}. Note=Interaction between G1 and G2 is essential for proper targeting of G1 to the Golgi complex, where virion budding occurs. {ECO:0000250}. |
| Subcellular location: | |
[Glycoprotein C]: Virion membrane {ECO:0000250|UniProtKB:P21401}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:P21401}. Host Golgi apparatus membrane {ECO:0000250|UniProtKB:P21401}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:P21401}. |
| Ptm: | |
Specific enzymatic cleavages in vivo yield mature proteins including NSm protein, Glycoprotein C, and Glycoprotein N. {ECO:0000250|UniProtKB:P21401}. |
| Similarity: | |
Belongs to the phlebovirus envelope glycoprotein family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.