UniProt functional annotation for P04905

UniProt code: P04905.

Organism: Rattus norvegicus (Rat).
Taxonomy: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
Function: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. The olfactory GST may be crucial for the acuity of the olfactory process.
Catalytic activity: RX + glutathione = HX + R-S-glutathione. {ECO:0000269|PubMed:8110735, ECO:0000269|PubMed:8664265}.
Subunit: Homodimer or heterodimer. {ECO:0000269|PubMed:1420139, ECO:0000269|PubMed:3011803, ECO:0000269|PubMed:8110735}.
Subcellular location: Cytoplasm.
Miscellaneous: Yb subclass selectively binds steroid hormones.
Similarity: Belongs to the GST superfamily. Mu family. {ECO:0000305}.
Similarity: Contains 1 GST C-terminal domain. {ECO:0000305}.
Similarity: Contains 1 GST N-terminal domain. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.