PDBsum entry 5sy7

Transcription/DNA

PDB id: 5sy7

Contents

Protein chains

276 a.a.

276 a.a.

DNA/RNA

PDB id:

5sy7

Name:

Transcription/DNA

Title:

Crystal structure of the heterodimeric npas3-arnt complex with hre dna

Structure:

Aryl hydrocarbon receptor nuclear translocator. Chain: a. Synonym: arnt protein,dioxin receptor,nuclear translocator,hypoxia- inducible factor 1-beta,hif1-beta. Engineered: yes. Neuronal pas domain-containing protein 3. Chain: b. Synonym: neuronal pas3,basic-helix-loop-helix-pas protein mop6,member of pas protein 6.

Source:

Mus musculus. Mouse. Organism_taxid: 10090. Gene: arnt. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: npas3, mop6. Synthetic: yes. Organism_taxid: 10090

Resolution:

4.20Å R-factor: 0.276 R-free: 0.361

Authors:

D.Wu,X.Su,N.Potluri,Y.Kim,F.Rastinejad

Key ref:

D.Wu et al. (2016). Npas1-Arnt and npas3-Arnt crystal structures implicat bhlh-Pas family as multi-Ligand binding transcription factors.. Elife, 5, . PubMed id: 27782878

Date:

10-Aug-16 Release date: 09-Nov-16

Protein chain

P53762  (ARNT_MOUSE) -  Aryl hydrocarbon receptor nuclear translocator from Mus musculus

Seq: 791 a.a.

Struc: 276 a.a.

Protein chain

Q9QZQ0  (NPAS3_MOUSE) -  Neuronal PAS domain-containing protein 3 from Mus musculus

Seq: 925 a.a.

Struc: 276 a.a.

DNA/RNA chains

G-G-C-T-G-C-G-T-A-C-G-T-G-C-G-G-G-T-C-G-T 21 bases

C-A-C-G-A-C-C-C-G-C-A-C-G-T-A-C-G-C-A-G-C 21 bases

Enzyme reactions

• Enzyme class: Chains A, B: E.C.?