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PDBsum entry 5r4z
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Hydrolase/hydrolase inhibitor
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PDB id
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5r4z
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PDB id:
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| Name: |
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Hydrolase/hydrolase inhibitor
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Title:
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Xchem fragment screen -- crystal structure of the bromodomain of the human atad2 in complex with n13605a
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Structure:
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Atpase family aaa domain-containing protein 2. Chain: a. Synonym: aaa nuclear coregulator cancer-associated protein,ancca. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: atad2, l16, pro2000. Expressed in: escherichia coli. Expression_system_taxid: 562
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Resolution:
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1.46Å
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R-factor:
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0.132
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R-free:
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0.162
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Authors:
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R.Talon,T.Krojer,M.Fairhead,R.Sethi,A.R.Bradley,A.Aimon,P.Collins, J.Brandao-Neto,A.Douangamath,N.Wright,E.Maclean,R.Zhang,A.Dias, P.E.Brennan,C.Bountra,C.H.Arrowsmith,A.Edwards,F.Von Delft
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Key ref:
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R.Talon
et al.
Xchem fragment screen.
To be published,
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Date:
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28-Feb-20
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Release date:
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13-May-20
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PROCHECK
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Headers
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References
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Q6PL18
(ATAD2_HUMAN) -
ATPase family AAA domain-containing protein 2 from Homo sapiens
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Seq:
Struc:
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1390 a.a.
130 a.a.*
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Key: |
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Secondary structure |
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*
PDB and UniProt seqs differ
at 4 residue positions (black
crosses)
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Links
