PDBsum entry 5l23

Protein binding

PDB id: 5l23

Contents

Protein chains

58 a.a.

17 a.a.

Ligands

PEG ×2

Waters ×99

PDB id:

5l23

Name:

Protein binding

Title:

Crystal structure of the complex between the n-terminal sh3 domain of crkii and a proline-rich ligand

Structure:

Adapter molecule crk. Chain: a. Fragment: unp residues 134-191. Synonym: proto-oncogenE C-crk,p38. Engineered: yes. C3g derived peptide. Chain: b. Engineered: yes

Source:

Mus musculus. Mouse. Organism_taxid: 10090. Gene: crk, crko. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 10090

Resolution:

1.77Å R-factor: 0.176 R-free: 0.210

Authors:

V.S.Bhatt,I.Krieger,J.Sacchettini,J.-H.Cho

Key ref:

V.S.Bhatt et al. Crystal structure of the complex between the n-Termin domain of crkii and a proline-Rich ligand. To be published, .

Date:

30-Jul-16 Release date: 07-Sep-16

Protein chain

Q64010  (CRK_MOUSE) -  Adapter molecule crk from Mus musculus

Seq: 304 a.a.

Struc: 58 a.a.

Protein chain

Q13905  (RPGF1_HUMAN) -  Rap guanine nucleotide exchange factor 1 from Homo sapiens

Seq: 1077 a.a.

Struc: 16 a.a.*

* PDB and UniProt seqs differ at 2 residue positions (black crosses)