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PDBsum entry 5kuh

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protein ligands Protein-protein interface(s) links
Signaling protein PDB id
5kuh

 

 

 

 

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Contents
Protein chains
636 a.a.
Ligands
LY5 ×4
PDB id:
5kuh
Name: Signaling protein
Title: Gluk2em with ly466195
Structure: Glutamate receptor ionotropic, kainate 2. Chain: a, b, c, d. Fragment: unp residues 32-544,667-908. Synonym: gluk2, glutamate receptor 6, glur6,gluk2, glutamate receptor 6, glur6. Engineered: yes. Mutation: yes
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: grik2, glur6. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108.
Authors: J.R.Meyerson,S.Chittori,A.Merk,P.Rao,T.H.Han,M.Serpe,M.L.Mayer, S.Subramaniam
Key ref: J.R.Meyerson et al. (2016). Structural basis of kainate subtype glutamate receptor desensitization. Nature, 537, 567-571. PubMed id: 27580033 DOI: 10.1038/nature19352
Date:
13-Jul-16     Release date:   07-Sep-16    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
P42260  (GRIK2_RAT) -  Glutamate receptor ionotropic, kainate 2 from Rattus norvegicus
Seq:
Struc:
 
Seq:
Struc:
908 a.a.
636 a.a.*
Key:    PfamA domain  Secondary structure
* PDB and UniProt seqs differ at 4 residue positions (black crosses)

 Enzyme reactions 
   Enzyme class: E.C.?
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

 

 
DOI no: 10.1038/nature19352 Nature 537:567-571 (2016)
PubMed id: 27580033  
 
 
Structural basis of kainate subtype glutamate receptor desensitization.
J.R.Meyerson, S.Chittori, A.Merk, P.Rao, T.H.Han, M.Serpe, M.L.Mayer, S.Subramaniam.
 
  ABSTRACT  
 
No abstract given.

 

 

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