UniProt functional annotation for Q5X5Q1

UniProt code: Q5X5Q1.

Organism: Legionella pneumophila (strain Paris).
Taxonomy: Bacteria; Proteobacteria; Gammaproteobacteria; Legionellales; Legionellaceae; Legionella.
 
Function: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. {ECO:0000255|HAMAP-Rule:MF_00131}.
 
Catalytic activity: Reaction=(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D- glyceraldehyde 3-phosphate + H2O + L-tryptophan; Xref=Rhea:RHEA:10532, ChEBI:CHEBI:15377, ChEBI:CHEBI:33384, ChEBI:CHEBI:57912, ChEBI:CHEBI:58866, ChEBI:CHEBI:59776; EC=4.2.1.20; Evidence={ECO:0000255|HAMAP-Rule:MF_00131};
Pathway: Amino-acid biosynthesis; L-tryptophan biosynthesis; L- tryptophan from chorismate: step 5/5. {ECO:0000255|HAMAP- Rule:MF_00131}.
Subunit: Tetramer of two alpha and two beta chains. {ECO:0000255|HAMAP- Rule:MF_00131}.
Similarity: Belongs to the TrpA family. {ECO:0000255|HAMAP- Rule:MF_00131}.

Annotations taken from UniProtKB at the EBI.