PDBsum entry 5k70

Cell adhesion

PDB id: 5k70

Contents

Protein chains

381 a.a.

Ligands

NAG-NAG-FUC

NAG-FUC ×3

NAG ×3

PO4 ×14

Waters ×62

PDB id:

5k70

Name:

Cell adhesion

Title:

Sidekick-2 immunoglobulin domains 1-4 h18r/n22s mutant

Structure:

Protein sidekick-2. Chain: a, b, c, d. Engineered: yes. Mutation: yes. Other_details: n-terminal residues gpaga are expression construct- derived and would be cleaved in the native protein

Source:

Mus musculus. Mouse. Organism_taxid: 10090. Gene: sdk2, kiaa1514. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293

Resolution:

2.70Å R-factor: 0.208 R-free: 0.243

Authors:

K.M.Goodman,S.Mannepalli,B.Honig,L.Shapiro

Key ref:

K.M.Goodman et al. (2016). Molecular basis of sidekick-Mediated cell-Cell adhesi specificity.. Elife, 5, . PubMed id: 27644106

Date:

25-May-16 Release date: 28-Sep-16

Protein chains

Q6V4S5  (SDK2_MOUSE) -  Protein sidekick-2 from Mus musculus

Seq: 2176 a.a.

Struc: 381 a.a.*

* PDB and UniProt seqs differ at 2 residue positions (black crosses)