PDBsum entry 5ixo

Signaling protein

PDB id

5ixo

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Contents

			Protein chain

					596 a.a.

			Ligands

					NAG-NAG ×3


					NAG ×3


					EDO ×2

			Metals

					_MG

			Waters ×78

PDB id:

5ixo

Links

Name:

Signaling protein

Title:

Crystal structure of the arabidopsis receptor kinase haesa lrr ectdomain (apo form).

Structure:

Receptor-like protein kinase 5. Chain: a. Fragment: ectodomain, residues 20-620. Synonym: protein haesa. Engineered: yes

Source:

Arabidopsis thaliana. Mouse-ear cress. Organism_taxid: 3702. Organ: flower. Tissue: abscission zone. Gene: rlk5, hae, at4g28490, f21o9.180. Expressed in: trichoplusia ni. Expression_system_taxid: 7111.

Resolution:

1.74Å

R-factor:

0.182

R-free:

0.222

Authors:

J.Santiago,M.Hothorn

Key ref:

J.Santiago et al. (2016). Mechanistic insight into a peptide hormone signaling mediating floral organ abscission.. Elife, 5, . PubMed id: 27058169

Date:

23-Mar-16

Release date:

20-Apr-16

PROCHECK

	Headers

	References

Protein chain

P47735 (RLK5_ARATH) - Receptor-like protein kinase 5 from Arabidopsis thaliana

Seq: Struc:

Seq: Struc:					999 a.a. 596 a.a.

Key:

Secondary structure



		Enzyme reactions

Enzyme class 1:

E.C.2.7.10.1 - receptor protein-tyrosine kinase.

[IntEnz] [ExPASy] [KEGG] [BRENDA]

Reaction:

L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H⁺

L-tyrosyl-[protein]	+	ATP	=	O-phospho-L-tyrosyl-[protein] Bound ligand (Het Group name = NAG) matches with 41.38% similarity	+	ADP	+	H(+)

Enzyme class 2:

E.C.2.7.11.1 - non-specific serine/threonine protein kinase.

[IntEnz] [ExPASy] [KEGG] [BRENDA]

Reaction:

1.	L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H⁺
2.	L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H⁺

L-seryl-[protein]	+	ATP	=	O-phospho-L-seryl-[protein] Bound ligand (Het Group name = NAG) matches with 41.38% similarity	+	ADP	+	H(+)

L-threonyl-[protein]	+	ATP	=	O-phospho-L-threonyl-[protein] Bound ligand (Het Group name = NAG) matches with 41.38% similarity	+	ADP	+	H(+)

Note, where more than one E.C. class is given (as above), each may correspond to a different protein domain or, in the case of polyprotein precursors, to a different mature protein.

Molecule diagrams generated from .mol files obtained from the KEGG ftp site