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UniProt functional annotation for Q16674 | ||
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| UniProt code: Q16674. |
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| Organism: | |
Homo sapiens (Human). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. |
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| Function: | |
Elicits growth inhibition on melanoma cells in vitro as well as some other neuroectodermal tumors, including gliomas. |
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| Subunit: | |
Interacts with FASLG. Interacts with TMIGD2. {ECO:0000269|PubMed:19807924, ECO:0000269|PubMed:22419821}. |
| Subcellular location: | |
Secreted. |
| Tissue specificity: | |
All malignant melanoma cell lines tested and infrequently in glioma cell lines. |
| Ptm: | |
May possess two intramolecular disulfide bonds. |
| Similarity: | |
Belongs to the MIA/OTOR family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.