PDBsum entry 5inw

Hormone

PDB id: 5inw

Contents

Protein chains

335 a.a.

31 a.a.

32 a.a.

Ligands

SO4

Waters ×2

PDB id:

5inw

Name:

Hormone

Title:

Structure of reaction loop cleaved lamprey angiotensinogen

Structure:

Putative angiotensinogen. Chain: a, b. Fragment: unp residues 26-443. Engineered: yes. Mutation: yes. C-terminal peptide of putative angiotensinogen. Chain: c, d. Fragment: unp residues 444-478. Engineered: yes

Source:

Lampetra fluviatilis. European river lamprey. Organism_taxid: 7748. Gene: agt. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

2.70Å R-factor: 0.208 R-free: 0.277

Authors:

H.Wei,A.Zhou

Key ref:

H.Wei et al. (2016). Heparin Binds Lamprey Angiotensinogen and Promotes Thrombin Inhibition through a Template Mechanism. J Biol Chem, 291, 24900-24911. PubMed id: 27681598 DOI: 10.1074/jbc.M116.725895

Date:

08-Mar-16 Release date: 05-Oct-16

Protein chains

C0MNC6  (C0MNC6_LAMFL) -  Putative angiotensinogen from Lampetra fluviatilis

Seq: 478 a.a.

Struc: 335 a.a.*

Protein chain

C0MNC6  (C0MNC6_LAMFL) -  Putative angiotensinogen from Lampetra fluviatilis

Seq: 478 a.a.

Struc: 31 a.a.

Protein chain

C0MNC6  (C0MNC6_LAMFL) -  Putative angiotensinogen from Lampetra fluviatilis

Seq: 478 a.a.

Struc: 32 a.a.

* PDB and UniProt seqs differ at 1 residue position (black cross)

DOI no: 10.1074/jbc.M116.725895

J Biol Chem 291:24900-24911 (2016)

PubMed id: 27681598

Heparin Binds Lamprey Angiotensinogen and Promotes Thrombin Inhibition through a Template Mechanism.

H.Wei, H.Cai, J.Wu, Z.Wei, F.Zhang, X.Huang, L.Ma, L.Feng, R.Zhang, Y.Wang, H.Ragg, Y.Zheng, A.Zhou.

ABSTRACT

No abstract given.