UniProt functional annotation for Q9FL12

UniProt code: Q9FL12.

Organism: Arabidopsis thaliana (Mouse-ear cress).
Taxonomy: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
 
Function: Serine protease that degrades the two-component response regulator ARR4 (PubMed:27274065, PubMed:29180814). Regulates ARR4 stability by targeting ARR4 in the nucleus for degradation. Acts upstream of ARR4 and regulates the activity of ARR4 in cytokinin and light-signaling pathways. ARR4 mediates the cross-talk between light and cytokinin signaling through modulation of the activity of phytochrome B (PubMed:27274065). {ECO:0000269|PubMed:27274065, ECO:0000269|PubMed:29180814}.
 
Subunit: Homooctamer formed by 4 homodimers (PubMed:29180814). Interacts with ARR4 (PubMed:27274065). {ECO:0000269|PubMed:27274065, ECO:0000269|PubMed:29180814}.
Subcellular location: Nucleus {ECO:0000269|PubMed:27274065}.
Tissue specificity: Expressed in roots, cotyledons, rosette leaves, cauline leaves, stems, flowers and siliques. {ECO:0000269|PubMed:27274065}.
Induction: Induced by trans-zeatin (at protein level). {ECO:0000269|PubMed:27274065}.
Similarity: Belongs to the peptidase S1C family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.