 |
PDBsum entry 5ign
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Transcription
|
PDB id
|
|
|
|
5ign
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PDB id:
|
|
|
|
| Name: |
|
Transcription
|
|
|
Title:
|
|
Crystal structure of human brd9 bromodomain in complex with lp99 chemical probe
|
|
Structure:
|
|
Bromodomain-containing protein 9. Chain: a, b. Fragment: unp residues 14-134. Synonym: rhabdomyosarcoma antigen mu-rms-40.8. Engineered: yes
|
|
Source:
|
|
Homo sapiens. Human. Organism_taxid: 9606. Gene: brd9, unq3040/pro9856. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
Resolution:
|
|
|
1.70Å
|
R-factor:
|
0.212
|
R-free:
|
0.243
|
|
|
Authors:
|
|
C.Tallant,P.G.K.Clark,L.C.C.Vieira,J.A.Newman,T.Krojer,G.Nunez- Alonso,S.Picaud,O.Fedorov,D.J.Dixon,F.Von Delft,C.H.Arrowsmith, A.M.Edwards,C.Bountra,P.E.Brennan,S.Knapp,Structural Genomics Consortium (Sgc)
|
|
Key ref:
|
|
C.Tallant
et al.
Crystal structure of brd9 bromodomain in complex with chemical probe.
To be published,
.
|
|
|
Date:
|
|
|
28-Feb-16
|
Release date:
|
30-Mar-16
|
|
|
|
|
|
|
PROCHECK
|
|
|
|
|
|
Headers
|
|
|
|
References
|
|
|
|
|
|
|
|
Q9H8M2
(BRD9_HUMAN) -
Bromodomain-containing protein 9 from Homo sapiens
|
|
|
|
Seq:
Struc:
|
|
|
|
597 a.a.
113 a.a.*
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Key: |
 |
PfamA domain |
|
|
 |
Secondary structure |
|
 |
CATH domain |
|
|
*
PDB and UniProt seqs differ
at 10 residue positions (black
crosses)
|
|
|
|
|
|
|
Links
