PDBsum entry 5ht1

Isomerase

PDB id

5ht1

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Contents

			Protein chain

					115 a.a.

			Waters ×20

PDB id:

5ht1

Links

Name:

Isomerase

Title:

Structure of apo c. Glabrata fkbp12

Structure:

Fk506-binding protein 1. Chain: a. Synonym: fkbp,peptidyl-prolyl cis-trans isomerase,ppiase,rapamycin- binding protein. Engineered: yes

Source:

Candida glabrata (strain atcc 2001 / cbs 138 / jcm 3761 / nbrc 0622 / nrrl y-65). Yeast. Organism_taxid: 284593. Strain: atcc 2001 / cbs 138 / jcm 3761 / nbrc 0622 / nrrl y-65. Gene: fpr1, cagl0k09724g. Expressed in: escherichia coli. Expression_system_taxid: 562

Resolution:

2.65Å

R-factor:

0.198

R-free:

0.263

Authors:

M.A.Schumacher

Key ref:

N.K.Tonthat et al. (2016). Structures of Pathogenic Fungal FKBP12s Reveal Possible Self-Catalysis Function. Mbio, 7, e00492. PubMed id: 27118592

Date:

26-Jan-16

Release date:

14-Sep-16

PROCHECK

	Headers

	References

Protein chain

Q6FMA3 (FKBP_CANGA) - FK506-binding protein 1 from Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138)

Seq: Struc:					114 a.a. 115 a.a.

Key:

PfamA domain

Secondary structure

CATH domain



		Enzyme reactions

Enzyme class:

E.C.5.2.1.8 - peptidylprolyl isomerase.

[IntEnz] [ExPASy] [KEGG] [BRENDA]

Reaction:

[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)

Peptidylproline (omega=180)	=	peptidylproline (omega=0)

Molecule diagrams generated from .mol files obtained from the KEGG ftp site

Added reference

	Mbio 7:e00492 (2016)
PubMed id: 27118592

Structures of Pathogenic Fungal FKBP12s Reveal Possible Self-Catalysis Function.
N.K.Tonthat, P.R.Juvvadi, H.Zhang, S.C.Lee, R.Venters, L.Spicer, W.J.Steinbach, J.Heitman, M.A.Schumacher.

ABSTRACT

No abstract given.