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UniProt functional annotation for A6T9C8 | ||
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| UniProt code: A6T9C8. |
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| Organism: | |
Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578). |
| Taxonomy: | |
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Klebsiella. |
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| Function: | |
Involved in the uric acid degradation pathway. Catalyzes the conversion of oxamate to oxalate. {ECO:0000269|PubMed:27303801}. |
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| Catalytic activity: | |
Reaction=H2O + oxamate = NH4(+) + oxalate; Xref=Rhea:RHEA:51512, ChEBI:CHEBI:15377, ChEBI:CHEBI:28938, ChEBI:CHEBI:30623, ChEBI:CHEBI:58363; EC=3.5.1.126; Evidence={ECO:0000269|PubMed:27303801}; |
| Biophysicochemical properties: | |
Kinetic parameters: Note=Kcat is 5.5 sec(-1) with oxamate as substrate. {ECO:0000269|PubMed:27303801}; |
| Subunit: | |
Heterodimer that consists of a 35.5 kDa large (alpha) subunit and a 20 kDa small (beta) subunit, which are synthesized from a single polypeptide. {ECO:0000269|PubMed:27303801}. |
| Ptm: | |
Cleaved by autocatalysis into a large (alpha) and a small (beta) subunit. {ECO:0000269|PubMed:27303801}. |
| Similarity: | |
Belongs to the gamma-glutamyltransferase family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.