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PDBsum entry 5h1k

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protein dna_rna Protein-protein interface(s) links
Splicing/RNA PDB id
5h1k

 

 

 

 

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Contents
Protein chains
674 a.a.
DNA/RNA
Waters ×1330
PDB id:
5h1k
Name: Splicing/RNA
Title: Crystal structure of wd40 repeat domains of gemin5 in complex with 13- nt u4 snrna fragment
Structure: Gem-associated protein 5. Chain: a, b. Fragment: unp residues 1-726. Synonym: gemin5. Engineered: yes. U4 snrna (5'-r( Gp Cp Ap Ap Up Up Up Up Up Gp Ap Cp A)-3'). Chain: c, d. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gemin5. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell: sf21. Synthetic: yes. Organism_taxid: 9606
Resolution:
1.90Å     R-factor:   0.172     R-free:   0.206
Authors: Y.Wang,W.Jin,C.P.Liu,N.Yang,M.Jin,Y.Cong,M.Wang,R.M.Xu
Key ref: W.Jin et al. (2016). Structural basis for snRNA recognition by the double-WD40 repeat domain of Gemin5. Genes Dev, 30, 2391-2403. PubMed id: 27881601 DOI: 10.1101/gad.291377.116
Date:
10-Oct-16     Release date:   23-Nov-16    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q8TEQ6  (GEMI5_HUMAN) -  Gem-associated protein 5 from Homo sapiens
Seq:
Struc:
 
Seq:
Struc:
 
Seq:
Struc:
1508 a.a.
674 a.a.
Key:    PfamA domain  Secondary structure

DNA/RNA chains
  G-C-A-A-U-U-U-U-U-G-A-C-A 13 bases
  C-A-A-U-U-U-U-U-G-A-C-A 12 bases

 

 
DOI no: 10.1101/gad.291377.116 Genes Dev 30:2391-2403 (2016)
PubMed id: 27881601  
 
 
Structural basis for snRNA recognition by the double-WD40 repeat domain of Gemin5.
W.Jin, Y.Wang, C.P.Liu, N.Yang, M.Jin, Y.Cong, M.Wang, R.M.Xu.
 
  ABSTRACT  
 
No abstract given.

 

 

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