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PDBsum entry 5gxh

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protein dna_rna ligands links
RNA binding protein/RNA PDB id
5gxh

 

 

 

 

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Contents
Protein chain
672 a.a.
DNA/RNA
Ligands
UNX ×3
GOL ×2
Waters ×317
PDB id:
5gxh
Name: RNA binding protein/RNA
Title: The structure of the gemin5 wd40 domain with aauuuuug
Structure: Gem-associated protein 5. Chain: a. Fragment: unp residues 1-739. Synonym: gemin5. Engineered: yes. Mutation: yes. RNA (5'-r( A Ap Up Up Up Up Up G)-3'). Chain: b. Synonym: u4 (118-125).
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gemin5. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: sf9. Synthetic: yes. Organism_taxid: 9606
Resolution:
1.80Å     R-factor:   0.163     R-free:   0.197
Authors: C.Xu,H.He,Y.Li,A.Dong,C.Bountra,C.H.Arrowsmith,A.M.Edwards,J.Min, Structural Genomics Consortium (Sgc)
Key ref: C.Xu et al. (2016). Structural insights into Gemin5-guided selection of pre-snRNAs for snRNP assembly. Genes Dev, 30, 2376-2390. PubMed id: 27881600 DOI: 10.1101/gad.288340.116
Date:
17-Sep-16     Release date:   26-Oct-16    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
Q8TEQ6  (GEMI5_HUMAN) -  Gem-associated protein 5 from Homo sapiens
Seq:
Struc:
 
Seq:
Struc:
 
Seq:
Struc:
1508 a.a.
672 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 1 residue position (black cross)

DNA/RNA chain
  A-U-U-U-U-U-G 7 bases

 

 
DOI no: 10.1101/gad.288340.116 Genes Dev 30:2376-2390 (2016)
PubMed id: 27881600  
 
 
Structural insights into Gemin5-guided selection of pre-snRNAs for snRNP assembly.
C.Xu, H.Ishikawa, K.Izumikawa, L.Li, H.He, Y.Nobe, Y.Yamauchi, H.M.Shahjee, X.H.Wu, Y.T.Yu, T.Isobe, N.Takahashi, J.Min.
 
  ABSTRACT  
 
No abstract given.

 

 

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