PDBsum entry 5gs0

Immune system

PDB id: 5gs0

Contents

Protein chains

663 a.a.

107 a.a.

122 a.a.

114 a.a.

107 a.a.

Ligands

NAG ×34

BMA ×4

MAN ×2

PDB id:

5gs0

Name:

Immune system

Title:

Crystal structure of the complex of tlr3 and bi-specific diabody

Structure:

Toll-like receptor 3. Chain: a, b. Fragment: ectodomain (unp residues 27-697). Engineered: yes. Light chain (anti-tlr3). Chain: c, e. Engineered: yes. Heavy chain (anti-tlr3). Chain: d, f.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: tlr3. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Mus musculus. Organism_taxid: 10090. Expression_system_taxid: 7111

Resolution:

3.28Å R-factor: 0.195 R-free: 0.248

Authors:

J.H.Kim,D.H.Song,S.J.Youn,J.W.Kim,G.Cho,H.Lee,J.O.Lee

Key ref:

J.H.Kim et al. (2016). Crystal structures of mono- and bi-specific diabodies and reduction of their structural flexibility by introduction of disulfide bridges at the Fv interface. Sci Rep, 6, 34515. PubMed id: 27682821 DOI: 10.1038/srep34515

Date:

13-Aug-16 Release date: 12-Oct-16

Protein chains

O15455  (TLR3_HUMAN) -  Toll-like receptor 3 from Homo sapiens

Seq: 904 a.a.

Struc: 663 a.a.

Protein chains

No UniProt id for this chain

Struc: 107 a.a.

Protein chains

No UniProt id for this chain

Struc: 122 a.a.

Protein chains

No UniProt id for this chain

Struc: 114 a.a.

Protein chains

No UniProt id for this chain

Struc: 107 a.a.

DOI no: 10.1038/srep34515

Sci Rep 6:34515 (2016)

PubMed id: 27682821

Crystal structures of mono- and bi-specific diabodies and reduction of their structural flexibility by introduction of disulfide bridges at the Fv interface.

J.H.Kim, D.H.Song, S.J.Youn, J.W.Kim, G.Cho, S.C.Kim, H.Lee, M.S.Jin, J.O.Lee.

ABSTRACT

No abstract given.