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PDBsum entry 5gmh

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protein ligands Protein-protein interface(s) links
Immune system PDB id
5gmh

 

 

 

 

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Contents
Protein chains
772 a.a.
Ligands
NAG-NAG ×3
RX8 ×2
NAG ×12
SO4 ×28
Waters ×653
PDB id:
5gmh
Name: Immune system
Title: Crystal structure of monkey tlr7 in complex with r848
Structure: Toll-like receptor 7. Chain: a, b. Fragment: unp residues 27-839. Synonym: uncharacterized protein. Engineered: yes. Mutation: yes
Source: Macaca mulatta. Rhesus macaque. Organism_taxid: 9544. Gene: tlr7. Expressed in: drosophila. Expression_system_taxid: 7215.
Resolution:
2.20Å     R-factor:   0.187     R-free:   0.225
Authors: Z.Zhang,U.Ohto,T.Shimizu
Key ref: Z.Zhang et al. (2016). Structural Analysis Reveals that Toll-like Receptor 7 Is a Dual Receptor for Guanosine and Single-Stranded RNA. Immunity, 45, 737-748. PubMed id: 27742543 DOI: 10.1016/j.immuni.2016.09.011
Date:
14-Jul-16     Release date:   02-Nov-16    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
B3Y653  (B3Y653_MACMU) -  Toll-like receptor 7 from Macaca mulatta
Seq:
Struc:
 
Seq:
Struc:
 
Seq:
Struc:
1049 a.a.
772 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 3 residue positions (black crosses)

 

 
DOI no: 10.1016/j.immuni.2016.09.011 Immunity 45:737-748 (2016)
PubMed id: 27742543  
 
 
Structural Analysis Reveals that Toll-like Receptor 7 Is a Dual Receptor for Guanosine and Single-Stranded RNA.
Z.Zhang, U.Ohto, T.Shibata, E.Krayukhina, M.Taoka, Y.Yamauchi, H.Tanji, T.Isobe, S.Uchiyama, K.Miyake, T.Shimizu.
 
  ABSTRACT  
 
No abstract given.

 

 

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