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UniProt functional annotation for Q9FII5 | ||
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| UniProt code: Q9FII5. |
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| Organism: | |
Arabidopsis thaliana (Mouse-ear cress). |
| Taxonomy: | |
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis. |
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| Function: | |
Acts with CLE41p and CLE44p peptides as a ligand-receptor pair in a signal transduction pathway involved in the regulation of procambium maintenance and polarity during vascular-tissue development (PubMed:17570668, PubMed:18812507, PubMed:27055373). Mediates repression of tracheary element differentiation and the promotion of procambial cells formation and polar division adjacent to phloem cells in the veins (PubMed:17570668, PubMed:18812507, PubMed:27055373). {ECO:0000269|PubMed:17570668, ECO:0000269|PubMed:18812507, ECO:0000269|PubMed:27055373}. |
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| Catalytic activity: | |
Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl- [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA- COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616, ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1; |
| Catalytic activity: | |
Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L- threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060, Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013, ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216; EC=2.7.11.1; |
| Subunit: | |
Interacts specifically with the mature peptides CLE41p and CLE44p, especially in the presence of SERK2 (PubMed:18812507, PubMed:27055373, PubMed:27449136, PubMed:27498761). Interacts with LURE1.2 (PubMed:26863186). {ECO:0000269|PubMed:18812507, ECO:0000269|PubMed:26863186, ECO:0000269|PubMed:27055373, ECO:0000269|PubMed:27449136, ECO:0000269|PubMed:27498761}. |
| Subcellular location: | |
Cell membrane {ECO:0000269|PubMed:18812507, ECO:0000269|PubMed:27498761}; Single-pass type I membrane protein {ECO:0000269|PubMed:18812507}. |
| Tissue specificity: | |
Widely expressed along the vascular strands. In roots and hypocotyls, confined to procambial cells. {ECO:0000269|PubMed:17570668, ECO:0000269|PubMed:18812507}. |
| Disruption phenotype: | |
Reduced procambial cells number, and adjacent or interspersed xylem and phloem formation. {ECO:0000269|PubMed:17570668, ECO:0000269|PubMed:18812507, ECO:0000269|PubMed:27055373}. |
| Similarity: | |
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. {ECO:0000255|PROSITE-ProRule:PRU00159}. |
Annotations taken from UniProtKB at the EBI.