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UniProt functional annotation for P32774 | ||
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| UniProt code: P32774. |
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| Organism: | |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). |
| Taxonomy: | |
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces. |
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| Function: | |
TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity. {ECO:0000269|PubMed:1918049}. |
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| Subunit: | |
TFIIA is a heterodimer composed of the large TOA1 and a small TOA2 subunits. Interacts with TBP. Interacts with TAF11. Interacts with KAP122. {ECO:0000269|PubMed:10525531, ECO:0000269|PubMed:11238911, ECO:0000269|PubMed:1918049, ECO:0000269|PubMed:8610010}. |
| Subcellular location: | |
Cytoplasm {ECO:0000269|PubMed:10525531}. Nucleus {ECO:0000269|PubMed:10525531}. Note=Imported to nucleus via interaction with KAP122. |
| Miscellaneous: | |
Present with 3910 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}. |
| Similarity: | |
Belongs to the TFIIA subunit 2 family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.