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PDBsum entry 5fg6

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protein ligands metals links
Transcription PDB id
5fg6

 

 

 

 

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Contents
Protein chain
118 a.a.
Ligands
EDO ×4
5XE
PO4
Metals
_NI
Waters ×190
PDB id:
5fg6
Name: Transcription
Title: Crystal structure of the bromodomain of human brd1 (brpf2) in complex with of-1 chemical probe
Structure: Bromodomain-containing protein 1. Chain: a. Synonym: br140-like protein,bromodomain and phd finger-containing protein 2. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: brd1, brl, brpf2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
1.10Å     R-factor:   0.182     R-free:   0.197
Authors: C.Tallant,D.R.Owen,B.S.Gerstenberger,P.Savitsky,A.Chaikuad,O.Fedorov, G.Nunez-Alonso,P.Filippakopoulos,F.Von Delft,C.H.Arrowsmith, A.M.Edwards,C.Bountra,S.Muller,S.Knapp
Key ref: C.Tallant et al. Crystal structure of the bromodomain of human brd1 (b in complex with of-1 chemical probe. To be published, .
Date:
20-Dec-15     Release date:   03-Feb-16    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
O95696  (BRD1_HUMAN) -  Bromodomain-containing protein 1 from Homo sapiens
Seq:
Struc:
 
Seq:
Struc:
 
Seq:
Struc:
1058 a.a.
118 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.?
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

 

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