PDBsum entry 5fg5

Transcription

PDB id: 5fg5

Contents

Protein chains

114 a.a.

108 a.a.

Ligands

5XF ×2

NO3

Waters ×252

PDB id:

5fg5

Name:

Transcription

Title:

Crystal structure of the bromodomain of human brpf1 in complex with pfi-4 chemical probe

Structure:

Peregrin. Chain: a, b. Synonym: bromodomain and phd finger-containing protein 1,protein br140. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: brpf1, br140. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

1.50Å R-factor: 0.168 R-free: 0.186

Authors:

C.Tallant,D.R.Owen,B.S.Gerstenberger,P.Savitsky,A.Chaikuad,O.Fedorov, G.Nunez-Alonso,P.Filippakopoulos,F.Von Delft,C.H.Arrowsmith, A.M.Edwards,C.Bountra,S.Muller,P.E.Brennan,S.Knapp

Key ref:

C.Tallant et al. Crystal structure of the bromodomain of human brpf1 i complex with pfi-4 chemical probe. To be published, .

Date:

20-Dec-15 Release date: 30-Dec-15

Protein chain

P55201  (BRPF1_HUMAN) -  Peregrin from Homo sapiens

Seq: 1214 a.a.

Struc: 114 a.a.

Protein chain

P55201  (BRPF1_HUMAN) -  Peregrin from Homo sapiens

Seq: 1214 a.a.

Struc: 108 a.a.

Enzyme reactions

• Enzyme class: Chains A, B: E.C.?