PDBsum entry 5emc

Transcription/DNA

PDB id: 5emc

Contents

Protein chains

70 a.a.

DNA/RNA

Metals

_ZN ×4

Waters ×184

PDB id:

5emc

Name:

Transcription/DNA

Title:

Transcription factor grdbd and smgre complex

Structure:

DNA (5'-d( Cp Cp Ap Gp Ap Ap (5Cm) p Ap Tp Cp Ap Tp Gp Tp Tp (5Cm)p Tp G)-3'). Chain: c. Engineered: yes. Glucocorticoid receptor. Chain: a, b. Fragment: unp residues 411-500. Synonym: gr,nuclear receptor subfamily 3 group c member 1. Engineered: yes.

Source:

Synthetic: yes. Synthetic construct. Organism_taxid: 32630. Homo sapiens. Human. Organism_taxid: 9606. Gene: nr3c1, grl. Expressed in: escherichia coli-pichia pastoris shuttle vector ppphis4.

Resolution:

2.30Å R-factor: 0.227 R-free: 0.261

Authors:

X.D.Su,T.Lian,J.Jin

Key ref:

J.Jin et al. The effects of cytosine methylation on general transc factors. To be published, .

Date:

06-Nov-15 Release date: 29-Jun-16

Protein chains

P04150  (GCR_HUMAN) -  Glucocorticoid receptor from Homo sapiens

Seq: 777 a.a.

Struc: 70 a.a.

DNA/RNA chains

C-C-A-G-A-A-5CM-A-T-C-A-T-G-T-T-5CM-T-G 18 bases

C-C-A-G-A-A-5CM-A-T-G-A-T-G-T-T-5CM-T-G 18 bases

Enzyme reactions

• Enzyme class: E.C.?