PDBsum entry 5elu

Signaling protein

PDB id: 5elu

Contents

Protein chains

91 a.a.

75 a.a.

Ligands

SO4 ×3

Waters ×102

PDB id:

5elu

Name:

Signaling protein

Title:

Isoform-specific inhibition of sumo-dependent protein-protein interactions

Structure:

Sumo-affirmer-s2b3. Chain: a. Engineered: yes. Other_details: masaatgvravpgnensleieelarfavdehnkkenallefvrvvkakeqvdltrfpvttmyyltleak dggkkklyeakvwvkgylleelkhnfkelqefkpvgdaaaahhhhhhhh. Small ubiquitin-related modifier 2. Chain: b. Synonym: sumo-2,hsmt3,smt3 homolog 2,sumo-3,sentrin-2,ubiquitin-like

Source:

Synthetic construct. Organism_taxid: 32630. Gene: phytocystatin. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Homo sapiens. Human. Organism_taxid: 9606. Gene: sumo2, smt3b, smt3h2.

Resolution:

2.35Å R-factor: 0.174 R-free: 0.207

Authors:

D.J.Hughes,C.Tiede,N.Hall,A.A.S.Tang,C.H.Trinh,K.Zajac,U.Mandal, G.Howell,T.A.Edwards,M.J.Mcpherson,D.C.Tomlinson,A.Whitehouse

Key ref:

D.J.Hughes et al. Isoform-Specific inhibition of sumo-Dependent protein-Protein interactions. To be published, . PubMed id: 29138295

Date:

05-Nov-15 Release date: 16-Nov-16

Protein chain

No UniProt id for this chain

Struc: 91 a.a.

Protein chain

P61956  (SUMO2_HUMAN) -  Small ubiquitin-related modifier 2 from Homo sapiens

Seq: 95 a.a.

Struc: 75 a.a.