PDBsum entry 5elj

Signaling protein

PDB id: 5elj

Contents

Protein chains

90 a.a.

75 a.a.

Waters ×75

PDB id:

5elj

Name:

Signaling protein

Title:

Isoform-specific inhibition of sumo-dependent protein-protein interactions

Structure:

Sumo-affirmer-s2d5. Chain: a. Engineered: yes. Small ubiquitin-related modifier 1. Chain: b. Synonym: sumo-1,gap-modifying protein 1,gmp1,smt3 homolog 3,sentrin, ubiquitin-homology domain protein pic1,ubiquitin-like protein smt3c, smt3c,ubiquitin-like protein ubl1. Engineered: yes

Source:

Synthetic construct. Organism_taxid: 32630. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Homo sapiens. Human. Organism_taxid: 9606. Gene: sumo1, smt3c, smt3h3, ubl1, ok/sw-cl.43.

Resolution:

1.98Å R-factor: 0.191 R-free: 0.236

Authors:

D.J.Hughes,C.Tiede,N.Hall,A.A.S.Tang,C.H.Trinh,K.Zajac,U.Mandal, G.Howell,T.A.Edwards,M.J.Mcpherson,D.C.Tomlinson,A.Whitehouse

Key ref:

D.J.Hughes et al. Isoform-Specific inhibition of sumo-Dependent protein-Protein interactions. To be published, . PubMed id: 29138295

Date:

04-Nov-15 Release date: 16-Nov-16

Protein chain

No UniProt id for this chain

Struc: 90 a.a.

Protein chain

P63165  (SUMO1_HUMAN) -  Small ubiquitin-related modifier 1 from Homo sapiens

Seq: 101 a.a.

Struc: 75 a.a.

Enzyme reactions

• Enzyme class: Chain B: E.C.?