PDBsum entry 5ek7

Transferase

PDB id: 5ek7

Contents

Protein chains

286 a.a.

Waters ×832

PDB id:

5ek7

Name:

Transferase

Title:

Structure of the autoinhibited epha2 jms-kd

Structure:

Ephrin type-a receptor 2. Chain: a, b. Fragment: cytoplasmic fragment residues 583-876. Synonym: epithelial cell kinase,tyrosine-protein kinase receptor eck. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: epha2, eck. Expressed in: escherichia coli. Expression_system_taxid: 562

Resolution:

1.90Å R-factor: 0.173 R-free: 0.205

Authors:

Q.Wei,J.Zheng

Key ref:

Q.Wei and j.zheng Structure of the autoinhibited epha2 jms-Kd. To be published, .

Date:

03-Nov-15 Release date: 30-Dec-15

Protein chains

P29317  (EPHA2_HUMAN) -  Ephrin type-A receptor 2 from Homo sapiens

Seq: 976 a.a.

Struc: 286 a.a.

Enzyme reactions

• Enzyme class: E.C.2.7.10.1 - receptor protein-tyrosine kinase.
• Reaction: L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H⁺

Molecule diagrams generated from .mol files obtained from the KEGG ftp site