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PDBsum entry 5eea

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protein dna_rna Protein-protein interface(s) links
Transcription PDB id
5eea

 

 

 

 

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Contents
Protein chains
61 a.a.
DNA/RNA
Waters ×518
PDB id:
5eea
Name: Transcription
Title: Structure of hoxb13-DNA(caa) complex
Structure: DNA (5'- d(p Tp Tp Gp Tp Gp Tp Tp Tp Tp Ap Tp Tp Gp Gp Gp Tp Cp C)-3'). Chain: d, c, h, k. Engineered: yes. DNA (5'- d(p Gp Gp Ap Cp Cp Cp Ap Ap Tp Ap Ap Ap Ap Cp Ap Cp Ap A)-3'). Chain: e, f, i, l. Engineered: yes. Homeobox protein hox-b13.
Source: Synthetic: yes. Synthetic construct. Organism_taxid: 32630. Homo sapiens. Human. Organism_taxid: 9606. Gene: hoxb13. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Resolution:
2.20Å     R-factor:   0.252     R-free:   0.297
Authors: E.Morgunova,Y.Yin,A.Jolma,A.Popov,J.Taipale
Key ref: E.Morgunova et al. Molecular basis of recognition of two distinct DNA se by a single transcription factor. To be published, . PubMed id: 29638214
Date:
22-Oct-15     Release date:   26-Oct-16    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q92826  (HXB13_HUMAN) -  Homeobox protein Hox-B13 from Homo sapiens
Seq:
Struc:
284 a.a.
61 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

DNA/RNA chains
  T-T-G-T-G-T-T-T-T-A-T-T-G-G-G-T-C-C 18 bases
  G-G-A-C-C-C-A-A-T-A-A-A-A-C-A-C-A-A 18 bases
  T-T-G-T-G-T-T-T-T-A-T-T-G-G-G-T-C-C 18 bases
  G-G-A-C-C-C-A-A-T-A-A-A-A-C-A-C-A-A 18 bases
  T-T-G-T-G-T-T-T-T-A-T-T-G-G-G-T-C-C 18 bases
  G-G-A-C-C-C-A-A-T-A-A-A-A-C-A-C-A-A 18 bases
  T-T-G-T-G-T-T-T-T-A-T-T-G-G-G-T-C-C 18 bases
  G-G-A-C-C-C-A-A-T-A-A-A-A-C-A-C-A-A 18 bases

 

 

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