| UniProt functional annotation for G0SCK6 | |||
| UniProt code: G0SCK6. |
| Organism: | Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719). | |
| Taxonomy: | Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes; Sordariomycetidae; Sordariales; Chaetomiaceae; Chaetomium. | |
| Function: | Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. {ECO:0000255|HAMAP-Rule:MF_03027}. | |
| Subunit: | Component of the NOP7 complex, composed of ERB1, NOP7 and YTM1. The complex is held together by ERB1, which interacts with NOP7 via its N-terminal domain and with YTM1 via a high-affinity interaction between the seven-bladed beta-propeller domains of the 2 proteins. The NOP7 complex associates with the 66S pre-ribosome. {ECO:0000255|HAMAP- Rule:MF_03027}. | |
| Subcellular location: | Nucleus, nucleolus {ECO:0000255|HAMAP- Rule:MF_03027}. Nucleus, nucleoplasm {ECO:0000255|HAMAP-Rule:MF_03027}. | |
| Similarity: | Belongs to the WD repeat BOP1/ERB1 family. {ECO:0000255|HAMAP-Rule:MF_03027}. | |
Annotations taken from UniProtKB at the EBI.