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PDBsum entry 5cq8
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Transcription
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PDB id
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5cq8
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PDB id:
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| Name: |
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Transcription
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Title:
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Crystal structure of the bromodomain of bromodomain adjacent to zinc finger domain protein 2b (baz2b) in complex with 4'- hydroxyacetophenone (sgc - diamond i04-1 fragment screening)
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Structure:
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Bromodomain adjacent to zinc finger domain protein 2b. Chain: a. Fragment: bromodomain, unp residues 1858-1972. Synonym: hwalp4. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: baz2b, kiaa1476. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Resolution:
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1.65Å
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R-factor:
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0.194
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R-free:
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0.222
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Authors:
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A.Bradley,N.Pearce,T.Krojer,J.Ng,R.Talon,M.Vollmar,B.Jose,F.Von Delft,C.Bountra,C.H.Arrowsmith,A.Edwards,S.Knapp,Structural Genomics Consortium (Sgc)
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Key ref:
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A.Bradley
et al.
Crystal structure of the second bromodomain of bromod adjancent to zinc finger domain protein 2b (baz2b) in complex with 4'-Hydroxyacetophenone (sgc - Diamond i0 fragment screening).
To be published,
.
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Date:
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21-Jul-15
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Release date:
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09-Sep-15
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PROCHECK
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Headers
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References
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Q9UIF8
(BAZ2B_HUMAN) -
Bromodomain adjacent to zinc finger domain protein 2B from Homo sapiens
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Seq:
Struc:
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2168 a.a.
115 a.a.*
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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*
PDB and UniProt seqs differ
at 2 residue positions (black
crosses)
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Links
