 |
PDBsum entry 5cq6
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Transcription
|
PDB id
|
|
|
|
5cq6
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PDB id:
|
|
|
|
| Name: |
|
Transcription
|
|
|
Title:
|
|
Crystal structure of the bromodomain of bromodomain adjacent to zinc finger domain protein 2b (baz2b) in complex with 2,6- pyridinedicarboxylic acid (sgc - diamond i04-1 fragment screening)
|
|
Structure:
|
|
Bromodomain adjacent to zinc finger domain protein 2b. Chain: a. Fragment: bromodomain, unp residues 1858-1972. Synonym: hwalp4. Engineered: yes
|
|
Source:
|
|
Homo sapiens. Human. Organism_taxid: 9606. Gene: baz2b, kiaa1476. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
Resolution:
|
|
|
1.97Å
|
R-factor:
|
0.191
|
R-free:
|
0.222
|
|
|
Authors:
|
|
A.Bradley,N.Pearce,T.Krojer,J.Ng,R.Talon,M.Vollmar,B.Jose,F.Von Delft,C.Bountra,C.H.Arrowsmith,A.Edwards,S.Knapp,Structural Genomics Consortium (Sgc)
|
|
Key ref:
|
|
A.Bradley
et al.
Crystal structure of the second bromodomain of bromod adjancent to zinc finger domain protein 2b (baz2b) in complex with 2,6-Pyridinedicarboxylic acid (sgc - Dia i04-1 fragment screening).
To be published,
.
|
|
|
Date:
|
|
|
21-Jul-15
|
Release date:
|
09-Sep-15
|
|
|
|
|
|
|
PROCHECK
|
|
|
|
|
|
Headers
|
|
|
|
References
|
|
|
|
|
|
|
|
Q9UIF8
(BAZ2B_HUMAN) -
Bromodomain adjacent to zinc finger domain protein 2B from Homo sapiens
|
|
|
|
Seq:
Struc:
|
|
|
|
2168 a.a.
115 a.a.*
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Key: |
 |
PfamA domain |
|
|
 |
Secondary structure |
|
 |
CATH domain |
|
|
*
PDB and UniProt seqs differ
at 2 residue positions (black
crosses)
|
|
|
|
|
|
|
Links
